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Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

Some skin diseases and their treatments can negatively affect male fertility.

Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.

A patient with Werner syndrome showed a range of aging-like symptoms and metabolic issues, underscoring the need for early detection and treatment.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.

Recent selection on immune response genes was identified across seven ethnicities.

Hashimoto thyroiditis is an autoimmune disease that can lead to an underactive thyroid and is treated with medication and sometimes diet changes or surgery.

The document concludes that the girl's hairlessness is likely inherited from her parents.

CCDC22 and CCDC93 are essential for root and root hair growth in Arabidopsis.

Dogs with dermatomyositis, especially Collies and Shetland Sheepdogs, need better treatments for their skin and muscle inflammation.

The document concludes that effectively managing PCOS requires a multifaceted approach.

Gene mutations can cause problems in male genital development.

Traditional Indian remedies are used for hair health, but more scientific evidence is needed to prove their safety and effectiveness.

Estrogen therapy can reduce skin aging but has cancer risks.

2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.

KRT14 gene variants cause dermatopathia pigmentosa reticularis, affecting nails, teeth, and hair.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

The protein RSL4 is crucial for making root hairs longer by controlling genes related to cell growth.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Environmental factors can cause mutations in skin proteins, leading to skin disorders.