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The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.

Apoptosis is crucial for healthy skin and treating skin diseases.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Hair follicle culture helps develop new treatments for hair loss.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.