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Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Toxic Shock Syndrome progresses quickly, often involves multiple organs, and is linked to Staphylococcus aureus toxins, with treatment options available but diagnostic challenges remaining.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Antidepressants may improve or resolve scalp dysesthesia in most patients.

Women with thinning hair have thinner hair strands than women without hair loss.

Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.

Most patients with chronic hair shedding did not progress to permanent hair loss, and one showed improvement with treatment.

Dupilumab for eczema may cause hair loss.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Zinc supplements can resolve skin issues caused by zinc deficiency.

Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.

Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Psoriasis can cause temporary or permanent hair loss.

Chronic hair shedding may be caused by less variation in hair growth times and might stop on its own after several years.

Etretinate has only moderate effects on localized scleroderma and lichen sclerosus.

Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.

Hair loss in women often doesn't follow a pattern, isn't linked to age, may be genetic, and can be related to thyroid issues or other health factors.

Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.

Most skin changes during pregnancy go away after giving birth.

Extended-release divalproex is better tolerated and more effective for seizures and psychiatric symptoms than delayed-release divalproex, but doesn't reduce hair loss.

Itraconazole was effective in treating unusual M. canis infections in only one of two HIV-infected men.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.