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This study discusses the transformative potential of gene editing technologies, such as CRISPR-Cas9, for personalized aesthetic interventions in dermatology, but highlights the need for rigorous safety measures, ethical considerations, and careful regulatory oversight before clinical application.

The researchers reviewed the status, challenges, and future prospects of CRISPR/Cas9-mediated gene-editing technology in livestock breeding, noting its benefits and highlighting concerns about low efficiency in inserting foreign genes and off-target effects.

In this review, researchers discussed the development, challenges, and future prospects of using CRISPR/Cas9 gene editing technology in livestock breeding, highlighting its current limitations in precise gene insertion and off-target effects, particularly in large livestock like cashmere goats.

This review explores the mechanisms, current products, challenges, and innovative approaches related to cosmetics for hair loss prevention and growth promotion, emphasizing the need for multidisciplinary cooperation to enhance product development and market success.

This review discusses advancements in plant cell culture technology for producing potent natural cosmetic ingredients and reports no new experimental results.

This review discusses recent advancements in omics and gene editing technologies for studying neuropeptides and receptors in fish, but reports no new experimental findings; the authors highlight the need for further research in this area.

In this research, OssDsign Catalyst™, a new nanosynthetic, silicate-enriched calcium phosphate bone graft substitute, is described as promoting early bone formation through its high silicate content and nanoscale structure, although no specific results are reported in the abstract.

This review provides guidance on using two-photon microscopy for real-time and long-term visualization of stem cell activity in live mice skin, focusing on its application in researching skin and stem cell biology.

This review discusses epigenetic mechanisms in tissue repair across species and summarizes recent CRISPR-based technologies as promising tools for studying and enhancing tissue regeneration, but reports no new experimental results.

CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.

This review highlights how nanotechnology enhances CRISPR-Cas9's potential for cancer treatment by improving delivery and stability, addressing key challenges like immunogenicity and delivery inefficiencies, and discusses recent advancements in stimuli-responsive nanoplatforms for precise genome editing.

This review found that among emerging technologies for skin anti-aging, stem cell therapies using recipient chimerism might be more beneficial than CRISPR-Cas9 and other current innovations, though further studies on safety and efficacy are needed.

This study developed new immortalized keratinocyte cell lines lacking COL7A1 using CRISPR/Cas9 technology, providing a valuable model to explore the biology and treatment options for recessive dystrophic epidermolysis bullosa.

This review covers advancements in skin repair and rejuvenation technologies, highlighting potential benefits of stem cell therapy, bioengineered skin substitutes, PRP, exosome therapies, and gene editing for conditions such as chronic wounds and genetic disorders, though challenges in accessibility, safety, and long-term effectiveness remain.

This review discusses gene editing techniques for breeding livestock, birds, and fish, concluding that they are key to advancing animal production by improving traits and efficiency.

This study demonstrates that genome-edited epidermal stem cells can continuously monitor blood glucose levels in vivo and potentially aid in diabetes treatment through skin somatic gene therapy.

This review discusses recent advances in stimuli-responsive nanoformulations for CRISPR-Cas9 delivery, highlighting their design rationales and potential biomedical applications, but reports no new experimental results.

This review highlights recent advances in CRISPR-based lineage tracing methods that can improve our understanding of skin stem cell behavior, regeneration, and disease, with potential applications in organoids and model organisms.

This commentary highlights the potential of using transgenic and genome-edited mouse models to validate findings from livestock genomic and multi-omic analyses, aiding in the understanding of economically significant animal traits.

This study found that engineered extracellular vesicles (293F-EGF-EV), enriched in EGF mRNA, significantly aided skin wound healing in vitro and in a rat model by promoting fibroblast activity and improving wound recovery through processes like angiogenesis and reduced scarring.

This review highlights recent advancements in androgenetic alopecia treatment, focusing on the dysregulated signaling pathways involved in hair follicle regeneration and exploring innovative therapeutic strategies, including small molecule modulators and gene editing technologies, which show promise in preclinical models.

This review highlights that liposomes offer a promising method for delivering CRISPR/Cas9 components for precise and efficient genetic modifications, with potential applications in correcting genetic diseases and enhancing immune cell function.

In this study, researchers found that the evolutionary and structural features of the oFGF5 gene in sheep may influence hair follicle development and hair growth regulation.

This study found that MSN-ceria nanomaterial accelerates cutaneous wound healing in rat models by reducing ROS levels and promoting collagen deposition, leading to improved tissue regeneration without significant scarring.

This study found that betibeglogene autotemcel significantly improved transfusion independence in 89% of patients with transfusion-dependent beta-thalassemia, although the high cost and manufacturing challenges may limit widespread adoption.

This review explores current strategies to enhance extracellular vesicle-based delivery of CRISPR/Cas systems, addressing efficiency challenges and suggesting future directions to bridge gene editing technologies with clinical applications.

This paper reviews current developments in humanized animal models for disease modeling and drug screening, highlighting advances in gene editing and stem cell technologies as key to creating more human-like models for research purposes.

This review examines structural elements and delivery methods for nonviral DNA- and RNA-based vectors used in gene editing, but reports no new experimental results.

This review examined the role of organoid technology in modeling genetic diseases, highlighting its promise for understanding disease pathology and developing tailored treatments by integrating genetic insights with advancements in regenerative medicine and biological engineering.

This study found that fibroblasts from Emery-Dreifuss muscular dystrophy patients with certain genetic mutations overexpress markers of fibrosis, and gene correction techniques reduced fibrogenic molecule expression in cell models, suggesting potential therapeutic applications.