research Removing All Obstacles: A Critical Role for p53 in Promoting Tissue Renewal
The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
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research CAG Repeat Testing of Androgen Receptor Polymorphism: Is This Necessary for the Best Clinical Management of Hypogonadism?
Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
research Gain-Of-Function Variants In The ODC1 Gene Cause A Syndromic Neurodevelopmental Disorder Associated With Macrocephaly, Alopecia, Dysmorphic Features, And Neuroimaging Abnormalities
ODC1 gene mutations cause a neurodevelopmental disorder with large head size, hair loss, and facial abnormalities.
research Pre-Clinical Cell-Based Therapy for Limbal Stem Cell Deficiency
Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.
research Dermatologic Adverse Events in Pediatric Patients Receiving Targeted Anticancer Therapies: A Pooled Analysis
Targeted anticancer therapies in children often cause skin side effects like rash and dry skin.
research Msx2 Supports Epidermal Competency During Wound-Induced Hair Follicle Neogenesis
The gene Msx2 is crucial for hair follicle regeneration during wound healing.
research Platelet-Rich Plasma and Cell Therapy
PRP and cell therapies may help with hair loss, but more research is needed.
research Future Horizons in Hair Restoration
New cell-based therapies may improve hair loss treatments in the future.
research No Evidence for THAP1/DYT6 Variants as Disease Modifiers in DYT1 Dystonia
THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.
research Skin and Hair Abnormalities of Cantu Syndrome: A Congenital Hypertrichosis Due to a Genetic Alteration Mimicking the Pharmacological Effect of Minoxidil
Cantu syndrome, which causes excessive hair growth and skin issues, is due to a mutation in the ABCC9 gene, and understanding this could help develop new treatments for hair diseases.
research Advancing Regenerative Cellular Therapies in Non-Scarring Alopecia
Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.
research Applications of Ultrasound-Mediated Gene Delivery in Regenerative Medicine
Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.
research Unlocking the Potential of the Secretome in Hair Growth Enhancement
Secretome-based therapies could improve hair growth better than current treatments.
research Spatiotemporal Expression and Haplotypes Identification of KRT84 Gene and Their Association with Wool Traits in Gansu Alpine Fine-Wool Sheep
The KRT84 gene is linked to better wool quality in Gansu Alpine Fine-wool sheep.
research Autologous Stem Cell-Derived Therapies for Androgenetic Alopecia: A Systematic Review of Randomized Control Trials on Efficacy, Safety, and Outcomes
Stem cell therapies show promise for hair regrowth in androgenetic alopecia.
research Exosomal MicroRNA-Based Therapies for Skin Diseases
miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
research The Association of Cytosine-Adenine-Guanine Repeat Polymorphism in the Androgen Receptor Gene with Nodulocystic Acne in Egyptian Patients
Certain gene variations are linked to severe acne in Egyptian patients and could guide treatment choices.
research Tfap2b Specifies an Embryonic Melanocyte Stem Cell That Retains Adult Multi-Fate Potential
The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
research Molecular Genetic Dissection of ILVEN Leads to Successful Targeted Therapy
Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.
research Highlights
Melatonin may help with nerve pain, a hepatitis C drug is effective but has side effects, a treatment for mouth sores works but can cause blood issues, ear reconstruction with an implant is safe, HIV transmission from mother to child in Taiwan is now 0% with treatment, certain blood problems are more common in people with a tongue condition, a gene and being overweight are linked to hair loss in some women, a new technique could reduce radiation for lung nodule patients, a hepatitis treatment may lower cancer recurrence after a procedure, and adding extra screening improves tuberculosis detection in patients with lung infections.
research Efficient Genome Editing Using CRISPR/Cas9 Ribonucleoprotein Approach in iPS Cells for Recessive Dystrophic Epidermolysis Bullosa
Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.
research Building a Functional Niche for Hair Follicle Stem Cells
Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
research Hair Restoration Surgery: Follicular Unit Grafting
Follicular unit grafting is a procedure used to treat hair loss, where small hair grafts are placed into the scalp, with future treatments likely to involve smaller incisions and cell-based therapies.
research Bioengineering Skin Using Mechanisms of Regeneration and Repair
Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
research Review Article: Dermatological Complications of Immunosuppressive and Anti-TNF Therapy in Inflammatory Bowel Disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via β-Catenin Activation
Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.
research Molecular Targeted Agents and Biologic Therapies for Non-Small Cell Lung Cancer
New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.
research Candidate Gene Analysis of Alopecia Areata in Jordanian Population of Arab Descent: A Case-Control Study
The study found that a specific genetic variation in the TNFα gene is significantly linked to Alopecia Areata in the Jordanian Arab population.
research Identification of Differentially Expressed Genes in Actinic Keratosis Samples Treated with Ingenol Mebutate Gel
Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.
research Feasibility of Repairing Skin Defects by VEGF165 Gene-Modified iPS-HFSCs Seeded on a 3D Printed Scaffold Containing Astragalus Polysaccharide
The new method using gene-modified stem cells and a 3D printed scaffold improved skin repair in mice.