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Involucrin gene expression is controlled by specific proteins and signaling pathways.

Sex steroids affect the MafB gene differently in male and female hamsters.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

Rat dermal papilla cells have unique genes crucial for hair growth.

The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.

VDR regulation varies by tissue and is crucial for its biological functions.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

The transition from growth to regression in Cashmere goat hair follicles involves changes in expression of genes related to keratin and cell differentiation.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

The enzyme pyruvate kinase M2 helps hair regrowth and could be a potential treatment for hair loss.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

Higher levels of the DP2 receptor may lead to hair loss.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

FGF-5 promotes Cashmere goat hair growth by increasing keratin genes and reducing certain LncRNA and target genes.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

SHBG may be a useful early indicator and treatment target for PCOS.