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Both mouse and rat models are effective for testing alopecia areata treatments.

Improving the environment and cell interactions is key for creating human hair in the lab.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Low-level laser therapy may improve hair regrowth and thickness for androgenetic alopecia, but more research is needed.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.

Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Hair follicles are valuable for regenerative medicine and wound healing.

Regulatory T cells are essential for normal and improved wound healing in mice.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Finasteride reverses early hair loss and promotes growth.

Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Erica multiflora plant extract can help hair grow by stimulating growth-related cells and triggering hair cycle changes.

EPR spectroscopy showed that spontaneous hair growth results in thicker skin and less pigmented hair than depilation-induced growth.