research Editorial Overview: Embroidering the Canvas of Life
The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.
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research 266 Myristoylphorbol Acetate (MPA) Enhances Metastasis Via Up-Regulation of Eph A2 Transcription Activity
MPA increases cancer spread by boosting Eph A2 activity.
research The Murine Hair Follicle Is a Melatonin Target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Cutaneous Signals of Immune System Disease
Skin issues can indicate immune system problems.
research Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
research Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib
A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.
research Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing
Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
research Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle
The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
research Local Circadian Clock Gates Cell Cycle Progression of Transient Amplifying Cells During Regenerative Hair Cycling
Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.
research Growth Factors and Cytokines in Hair Follicle Development and Cycling: Recent Insights from Animal Models and the Potentials for Clinical Therapy
Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.
research Inhibition of β-Catenin Signaling in Dermal Fibroblasts Enhances Hair Follicle Regeneration During Wound Healing
Blocking β-catenin in skin cells improves hair growth during wound healing.
research Stem Cells and the Circadian Clock
The circadian clock influences the behavior and regeneration of stem cells in the body.
research Dissecting the Microenvironment Around Biosynthetic Scaffolds in Murine Skin Wound Healing
Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
research Functional Hair Follicle Regeneration: An Updated Review
Hair follicle regeneration possible, more research needed.
research Whole-Cell Bioprocessing of Human Fetal Cells for Tissue Engineering of Skin
Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.
research Increased Lactate Dehydrogenase Activity Is Dispensable in Squamous Carcinoma Cells of Origin
High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.
research Role of Beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Kinetic Analysis of LY320236: Competitive Inhibitor of Type I and Non-Competitive Inhibitor of Type II Human Steroid 5α-Reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
research Dermal EZH2 Orchestrates Dermal Differentiation and Epidermal Proliferation During Murine Skin Development
Dermal EZH2 controls skin cell development and hair growth in mice.
research Runx Family Genes in Tissue Stem Cell Dynamics
Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
research Estrogen Modulates Mesenchymal-Epidermal Interactions in the Adult Nipple
Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
research Targeting Adult Mesenchymal Stem Cells Plasticity for Tissue Regeneration
Adult mesenchymal stem cells can help regenerate tissues and are promising for healing bones, wounds, and hair follicles.
research Cicatricial Alopecia: Early Diagnosis and Treatment Strategies
Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.
research NF-κB in Biology and Targeted Therapy: New Insights and Translational Implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research The Coenzyme A Precursor Pantethine Enhances Antitumor Immunity in Sarcoma
Pantethine may boost the immune system's ability to fight sarcoma.
research Extracellular Vesicles From 3D Cultured Dermal Papilla Cells Improve Wound Healing Via Krüppel-Like Factor 4/Vascular Endothelial Growth Factor A-Driven Angiogenesis
Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.
research DNA Methylation as an Epigenetic Memory Keeper During Skin Development and Regeneration
DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
research Mesenchymal Stem Cell-Derived Protein Extract Induces Periodontal Regeneration
MSC-protein helps regenerate gum tissue and bone.
research Dermal EZH2 Simultaneously Orchestrates Wnt/β-Catenin Signaling Dependent Dermal Differentiation and Retinoic Acid Signaling Dependent Epidermal Proliferation During Murine Skin Development
Ezh2 controls skin development by balancing signals for dermal and epidermal growth.
research Dermal EZH2 Simultaneously Orchestrates Dermal Differentiation and Epidermal Proliferation During Murine Skin Development
Dermal EZH2 controls skin cell growth and differentiation in mice.