research Antioxidant and Antiproliferative Activity of Finasteride Against Glioblastoma Cells
High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.
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300-330 / 1000+ resultsresearch Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research Repurposing of Drugs as Novel Influenza Inhibitors from Clinical Gene Expression Infection Signatures
Existing drugs, including a blood pressure medication, show promise as new treatments for influenza.
research Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion
The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
research Development and Evaluation of Antisense shRNA-Encoding Plasmid Loaded Solid Lipid Nanoparticles Against 5-Alpha Reductase Activity
The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
research Molecular, Immunological, Enzymatic and Biochemical Studies of Coproporphyrinogen Oxidase Deficiency in a Family with Hereditary Coproporphyria
A new gene mutation causes hereditary coproporphyria with reduced enzyme activity.
research Effect of Melatonin on Genes Including FGF5 Related to Hair Growth in Cashmere Goat Skin
Melatonin increased the activity of a hair growth gene in Cashmere goats.
research Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter
The system allows precise control of gene expression in mouse skin, useful for studying skin biology.
research Hormonal Activity in Commonly Used Black Hair Care Products: Evaluating Hormone Disruption as a Plausible Contribution to Health Disparities
Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.
research Differential Gene Expression in Post-Finasteride Syndrome Patients
Gene expression differences in PFS patients suggest a potential organic cause for symptoms.
research Gene Expression of Type 2 17β Hydroxysteroid Dehydrogenase in Scalp Hairs of Hirsute Women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research Normalization of Hair Growth in Sparse Fur-Abnormal Skin and Hair (SPF-ASH) Mice by Introduction of the Rat Ornithine Transcarbamylase (OTC) Gene
Introducing the rat OTC gene normalized hair growth in SPF-ASH mice.
research Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene
A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.
research Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats
FGF5 gene mutations cause long hair in domestic cats.
research Identification of a Cyclosporine-Specific P450 Hydroxylase Gene Through Targeted Cytochrome P450 Complement Disruption in Sebekia Benihana
A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.
research Blackcurrant Extract with Phytoestrogen Activity Alleviates Hair Loss in Ovariectomized Rats
Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.
research Polymorphism of CAG and GGN Repeats of Androgen Receptor Gene in Women with Polycystic Ovary Syndrome
Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.
research OVO Homolog-Like 1, a Target Gene of the Wnt/β-Catenin Pathway, Controls Hair Follicle Neogenesis
The OVOL1 gene, controlled by β-catenin, is crucial for creating hair follicles.
research Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes
Reducing FOXA2 in skin cells lowers their ability to grow hair.
research Expression and Analysis of TBX3 Gene in the Skin from Three Locations on Dun Mongolian Bider Horse
TBX3 gene affects horse coat color, with higher expression in darker areas.
research Dimorphic Regulation of the MafB Gene by Sex Steroids in Hamsters (Mesocricetus Auratus)
Sex steroids affect the MafB gene differently in male and female hamsters.
research A Case of MBTPS1-Related Disorder Due to Compound Heterozygous Variants in MBTPS1 Gene: Genotype-Phenotype Expansion and the Emergence of a Novel Syndrome
A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.
research High Migratory Activity of Dermal Sheath Cup Cells and Clinical Efficacy in Autologous Therapy for Hair Loss
Cells that move well may improve hair loss treatments by entering hair follicles.
research The FRZB Gene Regulates Hair Follicle Development in Rabbits via the Wnt/β-Catenin Signaling Pathway
The FRZB gene slows hair growth in rabbits.
research The Association of Cytosine-Adenine-Guanine Repeat Polymorphism in the Androgen Receptor Gene with Nodulocystic Acne in Egyptian Patients
Certain gene variations are linked to severe acne in Egyptian patients and could guide treatment choices.
research Correction of Ornithine Transcarbamylase (OTC) Deficiency in Spf-Ash Mice by Introduction of Rat OTC Gene
Introducing the rat OTC gene partially corrected OTC deficiency in mice.
research Effects of Platelet-Rich Plasma on In Vitro Hair Follicle Germ Preparation for Hair Regenerative Medicine
Platelet-rich plasma can potentially improve hair regeneration by increasing follicular gene expression and hair growth activity.
research The Human Papillomavirus Type 11 Upstream Regulatory Region Triggers Hair-Follicle-Specific Gene Expression in Transgenic Mice
The HPV type 11 region activates hair-specific gene expression in mice.
research The Promoter of an Androgen Dependent Gene in the Hamster Flank Organ
Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.
research Ishige Sinicola Extract Stimulates Osteoblast Proliferation and Differentiation via the Bone Morphogenetic Protein 2/Runt-Related Gene 2 Signaling Pathway
Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.