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AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

The effects of estrogen on human scalp hair growth are unclear and need more research.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Toxoplasma gondii infection may increase testosterone levels in males.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Valproic acid increases the risk of hair loss more than other drugs, especially in migraine patients, and lamotrigine may be a safer alternative.

Children are at risk of health issues from exposure to platinum group elements from car exhausts.

Caffeine improves hair growth, thickness, and reduces shedding.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

The document concludes that proper treatment and management of plaque psoriasis in adolescents can improve their quality of life.

The skin has about 230,000 touch-sensitive nerve fibers, with high concentrations in the hands and face.

Biologics for severe asthma have known side effects, but some new risks need more study.

Isotretinoin affects trace element levels and requires monitoring of liver and kidney functions.

Lipids are important for healthy hair, but their exact role is not fully understood and needs more research.

Women with PCOS often have sleep problems, including sleep apnea, which are linked to obesity and depression.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Products should be called 'sperm-safe' only after thorough, well-designed tests.