April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study introduces a hypothesis that elevated DHT at puberty may cause chronic thermal stress in specific scalp areas, potentially explaining Androgenetic Alopecia characteristics and guiding future research.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This paper introduces a hypothesis that elevated DHT at puberty may increase cerebral heat output, creating chronic thermal stress linked to androgenetic alopecia, and suggests this could be tested with MR thermometry.
November 2025 in “FEBS Open Bio” In this study, the researchers using Shh-GFP+/- mice found that cyclophosphamide-induced alopecia involves the JAK/STAT1 pathway, where STAT1 binds the Shh gene promoter, decreasing Shh-expressing cells in hair follicles. Treatment with JAK inhibitors helped rescue hair loss, implicating the JAK/STAT1 pathway in this process.
August 2024 in “Archives of Dermatological Research” Acne severity is not related to the type or severity of androgenetic alopecia.
Toupees improved perceived attractiveness, especially by older people, but had little effect on perceived self-assurance and health.
April 2024 in “Journal of Pakistan Association of Dermatologists” In this retrospective chart review at a dermatology clinic in Lagos, Nigeria, researchers reported that scalp hair loss was identified in 3.9% of cases, with alopecia areata as the most common type, predominantly affecting females and showing a mostly patchy pattern.
This study found that in Chinese Alashan Left Banner White Cashmere goats, guard hair length was positively correlated with guard hair diameter and down fiber length, but not with body weight at first combing.
November 2017 in “Dermatologic Clinics” Men are increasingly interested in cosmetic treatments that enhance masculinity and address aging without downtime, with tailored approaches for different ethnicities and a focus on hair restoration and body contouring.
January 2014 in “Theriogenology” This study found that blocking neurosteroid synthesis in the brain of pregnant sheep elevated HPA axis activity, suggesting neurosteroids play a vital role in moderating stress response.
January 1988 in “Nosotchu” This study observed a significant correlation between brain blood flow and hair magnesium and calcium levels in healthy elderly individuals, but no association between hair minerals and intelligence levels.
November 2022 in “Frontiers in Medicine” This study found no direct association between androgenetic alopecia and metabolic syndrome in the Chinese population, though AGA was closely linked with higher systolic blood pressure in men.
5 citations
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April 2019 in “Journal of The American Academy of Dermatology” This review discusses the complex nature of frontal fibrosing alopecia, suggesting it is a misnomer and possibly a subset of lichen planopilaris, but reports no new clinical results.
1 citations
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April 2024 in “Metabolites” In this study, researchers found that male and female APCHi mice exposed to ionizing radiation showed near-normal lipid and metabolite levels, suggesting activated protein C may offer some protective effects against radiation-induced damage affecting organ systems.
December 2024 in “Quality in Sport” This review found that modifying diet and lifestyle can significantly influence the progression and management of autoimmune diseases by reducing inflammation, supporting immune regulation, and addressing comorbidities, with potential benefits from anti-inflammatory diets, probiotics, and personalized approaches.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers created a comprehensive transcriptome map of human hair follicle compartments, identifying compartment-specific genes and providing a resource for potential therapeutic interventions.
January 2020 in “Journal of The European Academy of Dermatology and Venereology” This review summarizes recent developments in dermatology, including advancements in imaging techniques, biologics, and controversies in treatment, but presents no new clinical findings.
January 2025 in “International Journal of Trichology” In this 10-year study at a single hair referral center, pattern hair loss was the most common type of alopecia, affecting 67% of patients.
July 2023 in “International journal of trichology” In this randomized controlled trial, researchers found that Cellcurin therapy significantly increased hair density, terminal hair, and vellus hair counts in men and women with androgenetic alopecia, compared to minoxidil control, over 12 weeks.
April 2023 in “Nigerian Journal of Clinical Practice” In this study, androgenetic alopecia in Nigerians was associated with dyslipidemia, alcohol intake, and sedentary lifestyle, with severity linked to age, systolic blood pressure, and obesity.
38 citations
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September 2013 in “Therapeutic Drug Monitoring” This study found that increased hair cortisol levels among WIFN volunteers suggest higher chronic stress compared to those from a non-First Nation community, possibly linked to socioeconomic factors and poorer health.
28 citations
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August 2020 in “F1000Research” This review discusses the multifactorial pathogenesis of hidradenitis suppurativa and calls for more diverse, standardized clinical trials to improve treatment and understanding of dietary influences, reporting no new results.
13 citations
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December 2016 in “Egyptian Journal of Basic and Applied Sciences” This study found that patients with alopecia areata had significantly lower serum levels of 25-hydroxy vitamin D compared to control subjects.
11 citations
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July 2014 in “Clinical Rheumatology” This study found that Chinese female patients with systemic autoimmune diseases treated intravenously with cyclophosphamide were more likely to experience gastrointestinal discomfort, myelosuppression, and alopecia.
9 citations
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January 2016 in “Skin Pharmacology and Physiology” This study observed that estrogen receptor β and androgen receptor expressions in the skin decline with age, more noticeably under sun exposure, suggesting a role in skin aging.
9 citations
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October 2014 in “Experimental and Clinical Endocrinology & Diabetes” This study observed that acanthosis nigricans is highly prevalent in Latin American youths, especially at the knuckles, and may indicate early insulin resistance even in those with a normal BMI.
5 citations
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January 2014 in “BioMed Research International” This collection of papers reviews recent research on women's skin, focusing on hormonal influences, environmental impacts, and specific skin disorders, with no new clinical results reported.
4 citations
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March 2021 in “Experimental dermatology” Minoxidil increases nail growth more than biotin.
4 citations
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July 2015 in “Veterinary Dermatology” This study identified the expression of 5αR1 and 5αR3 enzymes in canine skin, which may advance understanding and treatment of alopecia X.
3 citations
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May 2008 in “Journal of Clinical Oncology” This study found that Pmab treatment may alter hair follicle growth cycles, leading to trichomegaly and hypertrichosis, but these effects do not correlate with other skin toxicities.
January 2025 in “Journal of Carcinogenesis” This study concluded that stromal vascular fraction and topical minoxidil both improved hair characteristics in male and female patients with androgenetic alopecia, but SVF offered a more satisfactory treatment experience.