855 citations
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June 2009 in “The Journal of Clinical Endocrinology & Metabolism” The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
11 citations
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November 2022 in “Journal of Endocrinological Investigation” In this study, gender-affirming hormonal treatment was associated with increased hair growth, acne, and alopecia prevalence in transgender individuals assigned female at birth, while opposite dermatological changes were observed in those assigned male at birth.
10 citations
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March 2018 in “Anais Brasileiros De Dermatologia” This study observed that androgenetic alopecia had a more significant negative impact on psychological parameters in females than males, with some differences in psychosexual outcomes based on clinical stages.
1 citations
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September 2020 in “Journal of the Endocrine Society” Men have worse COVID-19 outcomes than women due to genetic and hormonal differences.
July 2024 in “Biological and Clinical Sciences Research Journal” This review reports that transgender individuals undergoing hormonal therapy for gender transition face increased risks of cardiovascular disorders, brain tumors, changes in bone density, metabolic disorders, and other health issues, while highlighting the necessity of this therapy for gender transformation.
May 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that circulating testosterone affects baseline sex differences in voiding function in C57BL/6J mice, with prostate lobe mass having a lesser impact.
In this study, no significant difference was found between the efficacy of betamethasone dipropionate cream and placebo in treating alopecia areata in children, regardless of atopic status.
1 citations
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May 2025 in “Scientific Reports” In this study, researchers found no significant differences in serum levels of DHEAs, DHT, and testosterone between female patients with oral lichen planus and healthy controls, suggesting no neuroendocrine etiology linked to the condition.
In this study, researchers found no significant differences in the serum levels of DHEAs, DHT, and testosterone between female patients with oral lichen planus and healthy controls, suggesting no neuroendocrine etiology is associated with this condition.
January 2012 in “S. Karger AG eBooks” This article reviews treatment processes and outcomes for transsexualism, reporting improved quality of life and reduced gender dysphoria post-gender reassignment, though increased psychiatric risks remain compared to the general population.
81 citations
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July 2012 in “Translational Psychiatry” In this pilot study, no significant differences were observed between memantine and placebo groups in young adults with Down syndrome on the primary memory outcomes, but some improvement was noted in a secondary measure.
57 citations
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December 2018 in “JAMA Surgery” This systematic review suggests that current evidence does not support routinely discontinuing gender-affirming hormone treatments before surgery, especially testosterone and spironolactone, due to limited data on related perioperative risks.
40 citations
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November 2011 in “American Journal of Human Biology” In this study, stress experienced by transmen during early stages of gender transition was associated with reduced nocturnal blood pressure decline and increased C-reactive protein levels.
10 citations
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August 2020 in “International Journal of Andrology” This commentary examines whether 5α-reductase inhibitors are effective and safe for transfeminine and transmasculine individuals, highlighting the lack of efficacy and safety data in gender diverse populations and suggesting that clinicians discuss potential benefits and risks with patients considering their use.
7 citations
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January 2012 This study used artificial neural networks to predict hair loss by analyzing factors like gender and zinc deficiency, suggesting neural networks may effectively model hair loss prediction.
1 citations
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January 2018 in “Journal of clinical & experimental dermatology research” In this study, researchers found no significant difference in vitamin D levels between psoriasis patients and controls, suggesting no association between vitamin D deficiency and psoriasis.
January 2024 in “International Journal of Biology Sciences” This study in Iraq highlights significant links between COVID-19 outcomes and factors such as gender, education, age, and social behaviors, underscoring the importance of preventive measures and targeted interventions to enhance pandemic response.
August 2020 in “International Journal of Clinical Practice” In this study, researchers found no statistically significant difference in blood group distribution between patients with androgenetic alopecia and a healthy population.
1 citations
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July 2012 in “Nasza Dermatologia Online” This study found that patients with alopecia areata had significantly higher serum levels of IL-1α compared to healthy controls, with no significant difference observed in IL-1β levels.
151 citations
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May 2014 in “American Journal of Clinical Dermatology” This review concluded that oral finasteride for men and topical minoxidil for both genders have the most evidence supporting their effectiveness and safety for treating androgenetic alopecia.
58 citations
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December 2020 in “Mayo Clinic Proceedings” This paper discusses the variability in COVID-19 susceptibility and severity, emphasizing factors like biological differences and suggesting potential precision medicine approaches, but it reports no new clinical results.
29 citations
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November 2018 in “Journal of The European Academy of Dermatology and Venereology” This study found that anxiety-related traits significantly predict the impact of hair loss on quality of life across different alopecia types, with variations observed based on gender.
July 2021 in “Archives of Dermatological Research” This study found that serum GPER-1 levels were significantly higher in patients with androgenetic alopecia compared to healthy controls, suggesting a potential role in the condition's pathogenesis, independent of gender.
173 citations
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May 2001 in “Human reproduction update” This review discusses the role of oestrogens in stimulating growth hormone secretion and influencing linear bone growth in children, and reports no new clinical results; the authors suggest that oestrogens play a key role in pubertal growth spurts for both genders.
17 citations
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September 2024 in “The Indian Journal of Medical Research” This source explores long COVID syndrome and identifies risk factors like older age, female gender, and comorbidities such as diabetes. It mentions potential diagnostic biomarkers, highlights ongoing clinical trials, and emphasizes the importance of vaccines and rehabilitation in managing long COVID.
8 citations
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July 2024 in “PLoS ONE” In a comparative genomic study, researchers observed significant genetic differences among the three chemical races of the alga Botryococcus braunii, leading them to propose reclassifying these races as distinct species based on their unique genomic characteristics.
4 citations
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February 2025 in “Clinical Cosmetic and Investigational Dermatology” This study observed that hair characteristics significantly impact daily life, self-image, and well-being, varying by gender, ethnicity, and country, suggesting a need for interventions to address these psychological and social effects.
2 citations
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December 2022 in “Journal of toxicologic pathology” This review outlines the histological structures of the skin, highlighting species and regional differences in dermal absorption and obstacles encountered in toxicological assessments due to epidermal thickness variability, contact dermatitis reactions, and stem cell vulnerabilities.
July 2026 in “Journal of the Pakistan Medical Association” This study found that combining topical eflornithine with triple diode laser treatments in women with hirsutism led to a more rapid and nearly complete reduction of terminal hair after 6 months, though the intergroup differences were not significant at 6- and 12-month follow-ups.
March 2026 in “Dermatology Reports” This study found that frontal fibrosing alopecia had higher long-term remission rates compared to lichen planopilaris, highlighting differences in their clinical presentations and outcomes.