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270-300 / 1000+ resultsresearch The role of platelet-rich plasma in biomedicine: A comprehensive overview
This article reviews the potential applications, benefits, and limitations of platelet-rich plasma in medical practice and reports no new clinical results, emphasizing the need for standardized preparation and treatment protocols.
research 5α-reductase inhibitors impact prognosis of urothelial carcinoma
This retrospective cohort study found that patients using 5α-reductase inhibitors had reduced bladder cancer-related mortality compared to nonusers, with no significant effect on bladder cancer recurrence or upper tract urothelial carcinoma mortality.
research Oral Presentations: Abstracts of the Urological Society of Australia and New Zealand Annual Scientific Meeting, 25–28 February 2023, Melbourne, Australia
This study found that utilizing a clinical pharmacist in perioperative urological services reduced surgical cancellations and resident overtime while improving service efficiency and financial sustainability.
research Non-scarring Alopecias in Iranian Patients: A Histopathological Study With Hair Counts.
In this study on Iranian patients with non-scarring alopecia, researchers found that androgenetic alopecia was the most common subtype, with perifollicular inflammation observed more in males. They reported that transverse sectioning is generally sufficient for diagnosis, but combining with vertical sectioning provides more comprehensive information.
research Hair Manganese as a Marker of Cardiometabolic Status Rather than Coronary Artery Disease Severity—An Exploratory Pilot Study
This study found that hair manganese levels did not vary by acute coronary syndrome or stable coronary artery disease severity, but a modest, non-significant correlation with body mass index suggests a potential link between manganese homeostasis and cardiometabolic status that warrants further investigation.
research Centella asiatica L. Urb. Extracellular Vesicle and Growth Factor Essence for Hair and Scalp Health: A 56-Day Exploratory Randomized Trial
In this exploratory randomized controlled trial, participants using a combination of Centella asiatica-derived extracellular vesicles with recombinant growth factors showed significant improvements in hair thickness, density, length, and reduced hair loss and scalp sebum content after 56 days, compared to placebo.
research Poster Presentations at the 28th Joint Meeting of the International Society of Dermatopathology, March 5–6, 2025, Orlando, Florida, USA
In this study, researchers presented cases of cellular neurothekeoma in three male family members with early-onset in infancy, suggesting a potential genetic component and inheritance pattern, which deviates from the typical presentation seen mostly in women between 20–30 years.
research Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing
This study reports on a zinc-coordinated tri-enzyme nanogel system (Zn@nGSC) that mimics natural enzymatic processes to enhance enzymatic activity and cascade efficiency, showing potential in wound healing, hyperglycemia treatment, and antibacterial effects in a murine model of post-pancreatectomy.
research Exploring the molecular mechanism of Polygonum multiflorum in treating androgenic alopecia based on the methods of bioinformatics and molecular docking
This study explored the molecular mechanisms by which Polygonum multiflorum may treat androgenic alopecia, suggesting it influences cell apoptosis and inflammation through specific pathways, with potential application value pending further testing.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
This study reports that TFM-4AS-1, a selective androgen receptor modulator, promoted bone and muscle growth with reduced effects on reproductive organs in ovariectomized rats.
research Terminalia chebula retz. Fruit Extract Promotes Murine Hair Growth by Suppressing 5α-Reductase and Accelerating the Degradation of Dihydrotestosterone
This study suggests that Terminalia chebula fruit extract may promote hair growth in androgenetic alopecia by activating specific signaling pathways and inhibiting 5α-reductase, showing effectiveness comparable to finasteride.
research European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity
These guidelines recommend testing thyroid function in patients with obesity due to common hypothyroidism, and highlight that weight loss is crucial for addressing hormonal imbalances, with only modest weight loss benefits from treating endocrine disorders.
research Metformin treatment of polycystic ovary syndrome improves health-related quality-of-life, emotional distress and sexuality
This study found that metformin treatment improved health-related quality-of-life, emotional well-being, and sexual satisfaction among women with PCOS, correlated with weight loss and menstrual cycle normalization.
research Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone
Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.
research LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells
This study found that LGR5 may play a significant role in maintaining brain cancer stem-like cells and is associated with glioma progression and poor outcomes.
research Sex differences in arterial hypertension
This consensus document reviews current knowledge on sex differences in essential hypertension and identifies areas needing further research to improve sex-specific prevention and management strategies.
research Bald and Bad?
This study found that negative social attractiveness ratings for bald men by same-aged women occurred only when individuating information about the target was absent, while the physical attractiveness stereotype remained active at an implicit level.
research Poster Presentations
This case study reports a 70-year-old man with treatment-resistant pityriasis rubra pilaris achieving complete clinical remission with ustekinumab, adding to evidence supporting biologic therapy when TNF inhibitors are unsuitable.
research Emergence of the natural history of Myhre syndrome: 47 patients evaluated in the Massachusetts General Hospital Myhre Syndrome Clinic (2016–2023)
This study observed that among patients with Myhre syndrome, those with the SMAD4 gene variant p.Arg496Cys experienced fewer symptoms like hearing loss, while those with the p.Ile500Thr variant often had severe aortic hypoplasia, highlighting the diverse symptom progression and genetic factors of this rare condition.
research Understanding key symptoms, side effects, and impacts of HR+/HER2- advanced breast cancer: qualitative study findings
This study identified common symptoms and side effects experienced by women with hormone receptor-positive, HER2-negative advanced breast cancer, including fatigue, hair loss, and impacts on daily activities and mobility.
research Morphological, Macromolecular Structure and Hair Growth
research The Wound Reporting in Animal and Human Preclinical Studies (WRAHPS) Guidelines
In this study, researchers created the WRAHPS Guidelines to standardize the reporting of preclinical wound healing studies, aiming to improve transparency, enable comparative analysis, and support the development of human clinical trials for wound healing disorders.
research Effect of Patient Age on Platelet-Rich Plasma (PRP) and Fibrin Treatments for Skin Density and Thickness: A Single-Center Ultrasound Study
In this study, significant improvements in skin density and thickness, especially around the lower eyelid, were observed across all age groups using plasma fractions from a single blood draw, indicating that the therapy's effectiveness may be age-independent.
research Incretin-Based Drugs for Obesity: Common and Drug-Specific Reporting Patterns of Adverse Drug Reactions—A Comparative Disproportionality Analysis Using EudraVigilance Reports Integrating SmPC Data
This study analyzed safety data for semaglutide, liraglutide, and tirzepatide from the EudraVigilance database, identifying potential safety signals not listed in current SmPCs, such as optic ischemic neuropathy and pancreatitis, underscoring the importance of ongoing pharmacovigilance.
research Double Knockdown of the Androgen Receptor Target Genes DKK1 and SFRP1 Does Not Potentiate the Hair Growth-Promoting Effect of SFRP1 Silencing in Healthy Human Hair Follicles Ex Vivo
This study found that knocking down the gene SFRP1 in human hair follicles ex vivo prolonged the hair growth phase and increased keratinocyte proliferation, suggesting potential as a therapeutic target for maintaining hair growth in male pattern baldness, while DKK1 knockdown showed no effect.
research Microneedling for Androgenetic Alopecia: A Synergistic Strategy Enhancing Drug Delivery and Follicular Regeneration
This review indicates that while microneedling shows potential for managing androgenetic alopecia, particularly in combination with other treatments, the existing evidence is of low to moderate quality, and more robust trials are needed to confirm its clinical efficacy and safety.
research Photothermal conditioning of platelet-rich plasma: mechanisms and emerging applications in hair regeneration
This review found preliminary evidence suggesting that photothermal conditioning enhances the bioactivity of platelet-rich plasma, potentially improving hair regeneration outcomes, but highlights the need for standardized protocols and further studies to confirm its efficacy and safety.
research The Proportion of Catagen and Telogen Hair Follicles in Occipital Scalp of Male Androgenetic Alopecia Patients: Challenging the Established Dogma
This study examined hair follicles from 14 Caucasian males and found that catagen-phase follicles were more prevalent (7.5%) than previously reported, challenging the established view that telogen-phase follicles are more common.
research Short-Term Clinical Assessment of Treating Female Androgenic Alopecia with Autologous Stem Cells Derived from Human Hair Follicles
This study found that a single injection of autologous cell micrografts significantly improved hair condition in women with androgenetic alopecia six months post-treatment.