research First-Line Therapy with Gemcitabine and Paclitaxel in Locally Recurrent or Metastatic Breast Cancer: A Phase II Study
Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.
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research Gemcitabine in Combination with Vinorelbine in Elderly Patients with Anthracycline- and Taxane-Pretreated Metastatic Breast Cancer
The combination of gemcitabine and vinorelbine is effective and safe for treating elderly patients with advanced breast cancer previously treated with anthracyclines and taxanes.
research Gemcitabine Combined With Either Pemetrexed Or Paclitaxel In The Treatment Of Advanced Non-Small Cell Lung Cancer
Combining gemcitabine with paclitaxel is more effective than with pemetrexed for advanced lung cancer.
research Innovative Sequence of Docetaxel–Gemcitabine Based on Preclinical Data in the Treatment of Advanced Non-Small Cell Lung Cancer: A Phase I Study
The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.
research Efficacy and Toxicity of Pemetrexed or Gemcitabine Combined with Cisplatin in the Treatment of Patients with Advanced Non-Small Cell Lung Cancer
Pemetrexed with cisplatin is safer and more effective than gemcitabine with cisplatin for advanced lung cancer.
research Pegylated Liposomal Doxorubicin in the Treatment of Breast Cancer
PLD is an effective and safer alternative for treating breast cancer.
research Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs
Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.
research Neoadjuvant Therapy With Disitamab Vedotin in Treating Muscle-Invasive Bladder Cancer: A Case Report
A 68-year-old man with muscle-invasive bladder cancer (MIBC) and severe renal insufficiency, who was ineligible for cisplatin-based treatment, was successfully treated with neoadjuvant therapy using gemcitabine and Disitamab Vedotin (DV). The patient received three cycles of gemcitabine 1600 mg and DV 120 mg intravenously every three weeks. Imaging results showed a significant reduction in lesions, indicating a radiological partial response. Throughout the treatment, no significant adverse side effects were observed, making this combination a viable alternative for patients unable to tolerate platinum-based regimens.
research Malignant Epithelial Tumors: Part II. Therapy and Prevention
The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.
research Lentiginosis Within Plaques of Linear Atrophoderma of Moulin: A Twin-Spotting Phenomenon?
The document suggests a rare skin condition might be caused by a genetic phenomenon.
research Prevention and Treatment of Adverse Effects Related to Chemotherapy for Recurrent Ovarian Cancer
Nurses are crucial in managing chemotherapy side effects for ovarian cancer patients to improve their quality of life.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
research Management of Alopecia Due to Cancer Therapies
The document concludes that scalp cooling and treatments like minoxidil can help manage hair loss from cancer therapy.
research Are All Adverse Effects Undesirable? A Case of Chemotherapy-Induced Adverse Effect - An Exception!
Excessive eyelash growth from erlotinib may indicate positive tumor response and help treat madarosis.
research Folliculotropic Mycosis Fungoides: Prognosis and Treatment
Folliculotropic mycosis fungoides has a worse prognosis than other types, with survival rates varying significantly based on subtype and organ involvement.
research S-1 Induced Discoid Lupus Erythematosus-Like Lesions and Long-Term Complete Response for Para-Aortic Lymph Node Recurrence of Pancreatic Ductal Adenocarcinoma: A Case Report
S-1 treatment led to a complete response in pancreatic cancer with manageable side effects.
research A Prospective Observational Study on Drug Safety Monitoring and Pharmacoeconomics in Patients with Locally Advanced Unresectable NSCLC in a Tertiary Care Hospital
Carboplatin-paclitaxel is preferred for advanced lung cancer due to its balance of affordability and patient well-being.
research Colon Cancer Stem Cells: Promise of Targeted Therapy
Targeting colon cancer stem cells might lead to better treatment results.
research Anticancer Drugs in Surface Waters
Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.
research The PDGF/PDGFR Pathway as a Drug Target
The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Dermatological Adverse Events with Taxane Chemotherapy
Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
research Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.
research Cutaneous Toxicities of Cancer Therapy
Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.
research Drug Reactions Affecting Hair: Diagnosis
Some drugs can cause hair loss, change hair color and shape, or increase hair growth, and treatment may involve stopping the drug or using specific hair growth treatments.
research Docetaxel, Cisplatin and 5-Fluorouracil in Patients with Locally Advanced Unresectable Head and Neck Cancer: A Phase I-II Feasibility Study
The treatment combining docetaxel, cisplatin, and 5-FU is feasible and effective for advanced head and neck cancer.
research Chemotherapy-Induced Dermatological Toxicity: Frequencies and Impact on Quality of Life in Women’s Cancers. Results of a Prospective Study
Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.
research Red Ginseng Monograph
Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.
research Recent Advances in Microneedle Composites for Biomedical Applications: Advanced Drug Delivery Technologies
Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.
research Presentation, Impact and Prevention of Chemotherapy-Induced Hair Loss: Scalp Cooling Potentials and Limitations
Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.