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The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Imiquimod 5% cream reduced equine sarcoids in most cases.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Long-term fluticasone treatment does not harm the immune system in horses with heaves.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Menopause affects hair and skin; more research needed for treatment.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Some skin diseases and their treatments can negatively affect male fertility.

Finasteride gel effectively and safely reduces hair thickness in women with excessive hair growth.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.

Metformin helps improve menstrual irregularities and some hormone levels in PCOS patients, but not symptoms like excess hair, acne, or hair loss.