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Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Fungi-produced compounds can change plant root growth.

Targeted cancer therapies often cause serious skin problems that need careful management.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Low iron levels may be linked to some types of hair loss in women.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Too much androgen can cause hair loss; finasteride may help.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

TSH is usually the only test needed to check thyroid function in primary care.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

PLD is an effective and safer alternative for treating breast cancer.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.