research Advancements in Drug Repurposing: Examples in Psychiatric Medications
Old psychiatric drugs are increasingly being used for new purposes, and technologies like SmartCube® help create new drugs.
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research Novel Potential Therapeutic Targets of Alopecia Areata
New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.
research Obesity in Adults: Position Statement of Various Polish Medical Associations
The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.
research Efficacy of Albumin-Bound Paclitaxel Combined with Nedaplatin in Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma: A Single-Center Retrospective Observational Study
The combination therapy is effective and well-tolerated for treating esophageal cancer.
research The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome: A Review
Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
research Acne Syndromes and Mosaicism
Understanding how acne develops in different diseases could lead to new treatments.
research Abstracts from the 4th Annual Student Medical Summit
The document concludes that more research is needed to reduce frequent hospital visits, addiction medicine education improves with specific training, early breast cancer surgery findings are emerging, nipple smears are not very accurate, surgery for older melanoma patients doesn't extend life, a genetic condition in infants can often be treated with one drug, doctors are inconsistent with blood clot medication, a certain gene may protect against cell damage, muscle gene overexpression affects many other genes, and some mitochondrial genes are less active in mice with tumors.
research Paraproteinemic Keratopathy: Recognizing the Ocular Significance
Paraproteinemic keratopathy can show eye symptoms before other signs of disease, needing careful treatment and long-term follow-up.
research Polycystic Ovary Syndrome: Explaining the Gynecological Aspects and Treatment Options to Patients
Understanding Polycystic Ovary Syndrome (PCOS) and its causes can lead to effective treatments.
research Design of Nanocrystalline Suspension of Dutasteride for Intramuscular Prolonged Delivery
The nanocrystalline suspension effectively delivers dutasteride over time with minimal inflammation.
research Investigation of the Knowledge, Attitudes, and Perceptions Regarding the Utilization of Rosemary Among the Population in Jordan
Younger Jordanians know more about rosemary, often using it for hair and stomach issues.
research Exploring the Interplay Between Arsenic and Cutaneous Physiology, Pathology, and Regeneration
Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.
research Nanotechnology-Based Techniques for Hair Follicle Regeneration
Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
research Recent Advances in Neuropeptide-Related Omics and Gene Editing: Spotlight on NPY and Somatostatin and Their Roles in Growth and Food Intake of Fish
New tools show that in fish, NPY increases feeding and somatostatin decreases it.
research Is the Effect Worth the Risk? The Most Common Complaints During Oral Isotretinoin Anti-Acne Therapy and Controversies Around Its Adverse Effects
Most patients on isotretinoin for acne experience mild, dose-related side effects, but the connection to depression or bowel disease is uncertain.
research Common Causes of Pediatric Alopecia
Hair loss in children is often caused by scalp infections, immune disorders, hair pulling, stress, and requires careful treatment due to emotional effects.
research Effect of 5-Alpha Reductase Inhibitors in Animal Models of Parkinson's Disease
5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
research Understanding, Recognizing, and Managing Toxicities of Targeted Anticancer Therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
research Immuno-Endocrinology of COVID-19: The Key Role of Sex Hormones
Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.
research Dehydroepiandrosterone for Women in the Peri- or Postmenopausal Phase
DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
research Modeling the Pharmacodynamics of Nandrolone Doping Drug and Implications for Anti-Doping Testing
The document concludes that finasteride can reduce nandrolone detection in doping tests, suggesting frequent testing and setting metabolite level thresholds for detection.
research Finasteride Improves Motor, EEG, and Cellular Changes in Rat Brain in Thioacetamide-Induced Hepatic Encephalopathy
Finasteride helps brain function in rats with liver-related brain issues.
research Edible Oil-Producing Plants in the Sinja Valley, Jumla, Nepal
Traditional knowledge of edible oil-producing plants in Sinja Valley is declining due to outmigration and sociocultural changes.
research Glossary
research BAYONET Trial: Staged Combination With Encorafenib, Binimetinib, Plus Cetuximab Following Encorafenib Plus Cetuximab for BRAF V600E-Mutant Metastatic Colorectal Cancer
The combination treatment showed a higher response rate but no significant survival benefits.
research Hormonal Therapy in Dermatology
Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.
research Corticosteroids for the Treatment of Duchenne Muscular Dystrophy
Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.
research Pharmacological Interventions for Treating Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Some drugs may reduce prostatitis symptoms short-term with few side effects.
research Corticosteroids in the Treatment of Alopecia Totalis
Corticosteroids may effectively regrow hair in Alopecia Totalis with manageable side effects.
research Interventions for Female Pattern Hair Loss
Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.