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Dapsone improved pustular psoriasis in patients who didn't respond to other treatments and is considered a well-tolerated option.

Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.

The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.

Ethosomes improve drug delivery through the skin but may have side effects like irritation.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Aminopterin was somewhat effective in acute lymphoblastic leukemia in children but did not increase survival time.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Skin infections in cats are more common than thought, often affect young cats with allergies, and need better treatments.

A mother and son both had ulcerative colitis and alopecia, suggesting a genetic link in autoimmune disorders and successful treatment with cyclosporine.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

Recognizing and treating skin symptoms in essential thrombocythemia is crucial for patient quality of life.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Minoxidil in breast milk may harm nursing infants.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Severe digestive issues in DRESS need early endoscopy for better treatment.

Some chemicals absorbed through the skin can cause serious health problems.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Women experience various skin issues at different life stages, requiring careful treatment and awareness.

EGFR inhibitors can cause various skin issues during cancer treatment, and managing these is important for patient care.

Chemotherapy and cytokine therapy can cause various skin reactions, including hair loss and hypersensitivity.