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A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.

Using camphorated and mentholated chlorophenol in dental treatments can lead to severe gastrointestinal issues and hair and nail loss.

Hair loss in Cronkhite-Canada syndrome is reversible by treating the gut issues and doesn't need steroid treatment for the hair itself.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

Cannabinoids may help treat various skin conditions.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Frankincense may help treat COVID-19, but more research is needed.

Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.

Rituximab may be an effective treatment for Cronkhite-Canada syndrome with kidney disease.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Plant-derived extracellular vesicles show promise for treating diseases like cancer and inflammation.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Selenium is essential for health, but too much or too little can cause problems; blood selenium levels are a good measure of intake.

The YH complex, made from Astragalus membranaceus and Cinnamomum cassia, may help treat hair loss by promoting hair growth and follicle development.

Cholecystokinin may help reduce skin inflammation in psoriasis.

A man with Cronkhite-Canada syndrome improved significantly with immunosuppressive therapy.

Inflammation may cause nail issues in Cronkhite–Canada Syndrome.

A woman developed severe bladder inflammation after cancer treatment with Cytoxan.

Geranium plants have healing properties like fighting microbes, protecting the liver, reducing inflammation, and may help with viruses, stomach issues, and diabetes.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

A 75-year-old man lost weight, hair, and nails due to severe stomach and intestine inflammation.

A man with Cronkhite-Canada syndrome had all 20 nails detach but improved with treatment.

Cronkhite-Canada syndrome is rare, has a poor prognosis, and requires early diagnosis and ongoing treatment.

The 1891 epidemic skin disease was likely caused by arsenic poisoning, possibly from beer or fish.