219 citations
,
September 2016 in “American Journal of Psychiatry” This article reviews trichotillomania, highlighting its differences from OCD and recommending treatments like habit reversal therapy and specific medications, but reports no new clinical results.
44 citations
,
April 2023 in “Frontiers in Molecular Biosciences” This narrative review outlines the diverse symptoms and possible mechanisms behind long COVID, such as immune dysregulation and viral persistence, while discussing ongoing and potential treatments, highlighting the current lack of proven effective therapies.
41 citations
,
July 2018 in “Frontiers in Neurology” This study suggests that myotonic dystrophies may qualify as segmental progeroid disorders due to molecular and clinical similarities with typical progeroid syndromes.
14 citations
,
February 2022 in “Journal of Pain and Symptom Management” In this study, symptom clusters in people living with HIV were relatively consistent across different symptom experiences and may help develop targeted interventions for managing multiple symptoms simultaneously.
9 citations
,
August 2024 in “Pharmacological Reviews” This review summarized advancements in intestinal lymphatic drug delivery, emphasizing the evolving understanding of lymphatics as active players in health and disease, which has led to innovative therapeutic strategies and enhanced pharmacokinetic outcomes via this delivery route.
9 citations
,
December 2022 in “Phytomedicine” This review discusses the pharmacology, toxicology, and clinical efficacy of flavonoids and saponins, highlighting the need for more data on their pharmacokinetics, interactions, and toxicities as most research is still in vitro.
8 citations
,
September 2005 in “Practical diabetes” This article discusses management strategies for polycystic ovary syndrome, emphasizing the role of insulin resistance and the importance of addressing associated cardiovascular risk factors; it reports no new clinical results.
4 citations
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February 2022 in “International Journal of Molecular Sciences” This review discusses the similarities between myotonic dystrophy and aging, highlighting the role of cellular senescence in its pathophysiology, and reports no new clinical findings; the authors note potential anti-aging therapy applications.
2 citations
,
June 2025 in “Medicina” This retrospective study in pediatric patients with Sjögren's syndrome found consistent indications of tear film instability and identified systemic features like arthralgia, Raynaud's phenomenon, and frequent autoantibody positivity, underscoring the value of integrating clinical and ophthalmological assessments for early diagnosis.
2 citations
,
August 2022 in “Animals” This review discusses the potential use of essential oils and melatonin as nutraceuticals in dogs, highlighting their promising applications for addressing conditions like stress, anxiety, sleep disorders, and alopecia.
1 citations
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August 2025 in “International Journal of Molecular Sciences” This narrative review suggests that nutraceutical insulin-sensitizing agents like myo-inositol, alpha-lipoic acid, and vitamins may improve glycemic control and reduce inflammation in insulin resistance-related skin disorders; however, more robust long-term trials are needed to confirm these findings and establish treatment regimens.
April 2026 in “Diagnostics” This study found that skin changes in morbidly obese individuals are associated with underlying metabolic disturbances but are not currently valuable as independent tools for assessing metabolic risk or treatment response.
April 2025 in “Annals of Medicine” This study assessed the combination of compound glycyrrhizin and conventional treatments for alopecia areata and found it effective for promoting hair regrowth while being safe with mild adverse effects, based on a systematic review and meta-analysis of randomized controlled trials.
January 2024 in “Diagnostics” This literature review found that Long COVID is a complex condition involving multiple body systems, influenced by factors like pre-existing conditions and vaccination status, with differing manifestations and persistence, complicating diagnosis and treatment efforts.
January 2024 in “Journal of Ayurveda and integrative medicine” This paper discusses the potential of millets as a dietary intervention to help manage chemotherapy side effects in cancer patients, suggesting that their nutrient profile and various health benefits could support treatment without increasing medication burden.
This Special Issue in Nutrients investigates the nutritional strategies and outcomes in managing severe anorexia nervosa, with the aim of improving clinical practices for patients with serious or common physical conditions associated with the disease.
4 citations
,
December 2022 in “International Journal of Molecular Sciences” This review discusses the role of zinc and its transporters in skin health and disorders, providing an overview without presenting new clinical results.
151 citations
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May 2021 in “Frontiers in Medicine” This systematic review observed that a significant number of COVID-19 patients report long-term symptoms, including neurologic complaints and chronic fatigue, highlighting the presence of "post-COVID syndrome.
132 citations
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September 2021 in “Frontiers in Public Health” This study concluded that COVID-19 is a multisystem disease with both pulmonary and extrapulmonary manifestations, underscoring the importance of considering these symptoms for early diagnosis and infection control.
102 citations
,
January 2022 in “Mayo Clinic Proceedings” This review highlights that long-term health consequences of COVID-19, affecting multiple body systems, persist after acute infection, necessitating a comprehensive management approach that includes interdisciplinary care and lifestyle interventions to mitigate long-term damage.
98 citations
,
March 2019 in “Frontiers in immunology” This study concluded that heterozygous NFKB2 mutations lead to a distinct and severe form of primary immunodeficiency with early onset, primarily T cell-mediated autoimmunity, and impaired B-cell differentiation.
89 citations
,
March 2001 in “Endocrine practice” This article provides diagnosis and treatment guidelines for hyperandrogenic disorders in women but reports no new clinical results; it offers a summary of accepted scientific information and suggestions for clinical practice.
59 citations
,
August 2021 in “Frontiers in Endocrinology” This review discusses the roles and therapeutic effects of GLP-1 receptor agonists on the nervous, cardiovascular, and endocrine systems, but reports no new clinical results, emphasizing the need for further research on their impact on metabolism and tumor relationships in type 2 diabetes patients.
44 citations
,
September 2020 in “International Journal of Molecular Sciences” This review discusses the disruption of hormonal and metabolic rhythms in polycystic ovary syndrome and explores potential drug targets to address its molecular causes, without providing new clinical results.
34 citations
,
June 2015 in “Journal of cardiovascular pharmacology and therapeutics” This article discusses the use of direct vasodilators and sympatholytic agents in hypertension management, highlighting their utility in specific cases like refractory hypertension and heart failure, but reports no new clinical results.
25 citations
,
October 2018 in “Journal of Mind and Medical Sciences” This review discusses the introduction of new oral anticoagulants for atrial fibrillation and highlights their safety and the development of reversal agents, but reports no new clinical findings.
21 citations
,
September 2015 in “International journal of gynaecology and obstetrics” This article discusses safety, management, and adverse effects of chemotherapy in gynecological malignancies without reporting new clinical data, and emphasizes the importance of thorough patient and drug selection.
20 citations
,
January 2023 in “Frontiers in Immunology” This review discusses the role of skin-associated adipocytes in modulating skin immune responses and infection, reporting no new experimental results.
12 citations
,
May 2022 in “Plants” This review highlights the potential of nano-phytopharmaceuticals in improving the bioavailability and efficacy of phytochemicals for treating locomotor, dermal, reproductive, and urinary tract disorders, but notes that more clinical and preclinical research is needed to establish their safety and efficacy for human use.
8 citations
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January 2020 in “Evidence-based Complementary and Alternative Medicine” This study found that Cinobufacin combined with chemotherapy improved clinical outcomes in breast cancer patients and reduced certain side effects compared to chemotherapy alone.