59 citations,
February 2003 in “Veterinary Dermatology” Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
16 citations,
January 2013 in “Pediatric Gastroenterology Hepatology & Nutrition” Azathioprine caused side effects in over half of the Korean pediatric inflammatory bowel disease patients, requiring close monitoring.
16 citations,
March 2011 in “Pediatric diabetes” Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.
15 citations,
September 1992 in “The Lancet” Stopping minoxidil caused significant hair loss, but regrowth occurred after resuming use.
15 citations,
May 1966 in “The Journal of Urology” A woman developed severe bladder inflammation after cancer treatment with Cytoxan.
13 citations,
July 2010 in “Journal of The American Academy of Dermatology” A man with Cronkhite-Canada syndrome had all 20 nails detach but improved with treatment.
12 citations,
June 2023 in “Journal of trace elements in medicine and biology” Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.
12 citations,
January 2018 in “Acta pharmaceutica sciencia” Solid lipid nanoparticles can improve how well drugs that don't dissolve in water work and are safe.
11 citations,
October 2020 in “Sultan Qaboos University medical journal” Bariatric surgery helps with weight loss but can cause complications and nutritional deficiencies.
8 citations,
April 2017 in “American Journal of Dermatopathology” Inflammation may cause nail issues in Cronkhite–Canada Syndrome.
7 citations,
December 2013 in “The Journal of Dermatology” A woman's hair turned gray and fell out after starting a cancer drug called imatinib mesylate.
3 citations,
September 1994 in “Indian Journal of Dermatology, Venereology and Leprology” Hair loss in women was often caused by stress, illness, childbirth, or low hemoglobin, with most cases being telogen effluvium.
2 citations,
August 2017 in “British Journal of Dermatology” Hair loss in Cronkhite-Canada syndrome may be due to an autoimmune response.
1 citations,
August 2023 in “Frontiers in immunology” Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.
1 citations,
March 2022 in “Frontiers in Medicine” This case report discusses a 67-year-old man with Cronkhite-Canada syndrome (CCS) who developed early esophageal carcinoma, a rare comorbidity. The patient was treated with endoscopic submucosal dissection for the esophageal lesion and endoscopic mucosal resection for colon polyps, followed by glucocorticoid therapy. The treatment was successful, with no recurrence of esophageal carcinoma and a decrease in gastrointestinal polyps over an 18-month follow-up. The case highlights the importance of regular endoscopic surveillance in CCS patients due to the potential for malignant transformation.
1 citations,
October 2021 in “Al-Rafidain journal of medical sciences.” Platinum compounds used in cancer treatment can cause serious side effects like organ damage and hair loss.
1 citations,
April 2019 in “Acta Medica Philippina” Azathioprine may help treat severe alopecia areata, but more research is needed.
1 citations,
February 2018 in “Orthopedics and rheumatology” Combining Western chemotherapy with Traditional Chinese Medicine can reduce side effects and improve immune response in treating bone and soft tissue tumors.
1 citations,
July 2014 in “Current psychiatry” Patients on mood stabilizers need regular health checks, but many aren't monitored properly.
April 2024 in “Remedium Journal about the Russian market of medicines and medical equipment” Pharmacy workers need more education to better help people with hair loss.
May 2023 in “Journal of Applied Cosmetology” The Annurca apple supplement significantly improved hair growth in people with hair loss.
December 2019 in “European journal of internal medicine” A Laotian man with unusual skin changes and multiple growths in his gut was diagnosed with Cronkhite-Canada Syndrome and improved with nutritional and immune-based treatments.
October 2014 in “Archives of disease in childhood” Childhood cancer diagnosis leads to long-term physical and emotional health issues in parents.
November 2013 in “International Journal of Dermatology” New skin lesions on the scrotum or vulva in patients with a history of internal cancer could indicate rare skin metastasis.
January 2001 in “대한피부과학회지” Minipulse therapy with betamethasone effectively promotes hair regrowth in alopecia areata with fewer side effects.
January 2001 in “대한피부과학회지” Oral minipulse therapy with betamethasone effectively promotes hair regrowth in alopecia areata with fewer side effects.
2 citations,
August 2022 in “World Journal of Clinical Cases” Cronkhite-Canada syndrome (CCS) is a rare disorder characterized by gastrointestinal polyps and ectodermal lesions, including alopecia. This case report describes an elderly female with CCS who experienced significant symptom improvement with albumin supplementation and prednisone. Exome sequencing of her colorectal adenoma revealed novel somatic mutations in USP24, KCNQ5, and FKBP10 genes, and elevated copy numbers in HPSE2, SPATA7, and ZC3H18 genes, suggesting potential genetic mechanisms underlying CCS. Further research with larger sample sizes is needed to confirm these findings and understand the disease's etiology.
December 2019 in “The American Journal of Gastroenterology” Small bowel lesions in Cronkhite-Canada syndrome persist despite steroid treatment.
63 citations,
September 2020 in “Frontiers in Microbiology” Probiotics show promise for health benefits but need more research to understand how they work.
1 citations,
July 2017 in “PubMed” Two patients with Cronkhite-Canada syndrome achieved remission after treatment.