research Identification of MicroRNAs Involved in Growth Arrest and Cell Death in Hydrogen Peroxide-Treated Human Dermal Papilla Cells
Targeting specific miRNAs may help treat hair follicle issues caused by hydrogen peroxide.
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research LncRNA-XIST Promotes Dermal Papilla Induced Hair Follicle Regeneration by Targeting miR-424 to Activate Hedgehog Signaling
XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.
research Upregulation of Interfollicular Epidermal and Hair Infundibulum β-Catenin Expression in Gsdma3 Mutant Mice
Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.
research Comparative Efficacy and Safety of Janus Kinase Inhibitors Used in Alopecia Areata: A Systematic Review and Meta-Analysis
Baricitinib and deuruxolitinib are effective for treating alopecia areata, but their efficacy depends on the dose.
research Distinct Expression Profile of Stem Cell Markers, LGR5 and LGR6, in Basaloid Skin Tumors
LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.
research Dual Inhibitors of Urease and Carbonic Anhydrase-II from Iris Species
Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.
research Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant
Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.
research LncRNA-599547 Contributes to the Inductive Property of Dermal Papilla Cells in Cashmere Goats Through miR-15b-5p/Wnt10b Axis
A specific RNA in cashmere goats helps improve hair growth by interacting with certain molecules.
research TR3 Is Preferentially Expressed by Bulge Epithelial Stem Cells in Human Hair Follicles
TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
research Epimedium Brevicornum Maxim Extract Enhances Melanin Biosynthesis and Melanosome Biogenesis/Transfer
Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.
research RNA Sequence Analysis of Dermal Papilla Cells’ Regeneration in 3D Culture
3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
research Non-Dietary Scurvy With Relapse Symptoms After Stopping Oral Vitamin C Supplementation
A 3-year-old girl developed scurvy symptoms that improved with vitamin C but relapsed when supplementation stopped.
research HIF-2α/ARNT Complex Regulates Hair Development via Induction of p21 Waf1/Cip1 and p27 Kip1
The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.
research The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis
A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.
research Erythroid Differentiation Regulator 1 as a Novel Biomarker for Hair Loss Disorders
Erdr1 could be a new marker for diagnosing hair loss.
research Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database
Biologics for severe asthma have known side effects, but some new risks need more study.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Global Landscapes of Human Phenotypic Variation in Inherited Traits
Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.
research Characterization And Neural Differentiation In Vitro Of Stem Cells From Human Deciduous Tooth Pulp
Dental pulp stem cells might not reliably become neurons.
research Blockade of S100A3 Activity Inhibits Murine Hair Growth
Stopping S100A3 activity slows down hair growth in mice.
research Micronutrients for Hair and Nails: A Review of Their Impact on Health
Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.
research Pilose Antler Extracts Promote Hair Growth in Androgenetic Alopecia Mice by Activating Hair Follicle Stem Cells via the AKT and Wnt Pathways
Pilose antler extracts help hair growth by activating hair follicle stem cells.
research Phytochemicals: An Herbal Remedy for Alopecia
Plant-based treatments can effectively and safely treat hair loss.
research The Evaluation of IL-4 Intron 3 VNTR and TNF-α (rs1799964) Gene Polymorphisms in Egyptian Patients with Alopecia Areata: A Case-Control Study
These specific gene polymorphisms are not linked to Alopecia Areata in Egyptians.
research AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis
AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going
Innovative methods are reducing animal testing and improving biomedical research.
research A Human Prenatal Skin Cell Atlas Reveals Immune Cell Regulation of Skin Morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Formulation and Evaluation of Herbal Hair Serum: A Review
Herbal hair serum promotes natural hair growth and maintains healthy hair.
research Evaluation of Serum UL16 Binding Protein 3 in Patients with Tinea Capitis
ULBP3 levels are higher in Tinea capitis patients and may help predict the disease's severity.
research Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus
Melatonin affects certain genes and pathways involved in cashmere goat hair growth.