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Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Two elderly men developed scalp inflammation after using a gel for skin lesions, which healed with treatment except for some permanent hair loss.

Male pattern hair loss may have evolved to promote younger fathers for offspring health and survival, encouraging monogamy and paternal nurturing.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Finasteride's solubility improves with native y-CDs, enhancing hair loss treatment and reducing side effects.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Jojoba oil is highly valued for its diverse medicinal and industrial uses.

Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.

GLI2 increases follistatin production in human skin cells.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.