research Effects of In Utero Exposure to D-004, a Lipid Extract from Roystonea Regia Fruits, in the Male Rat: A Comparison with Finasteride
D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.
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research Adsorptive Cathodic Stripping Determination of Minoxidil in Pharmaceutical, Cream, and Shampoo Products
Researchers developed a sensitive method to measure minoxidil in various products with high accuracy.
research Testosterone Treatment in Women: An Overview
Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
research Proscar (Finasteride) Inhibits 5α-Reductase Activity in the Ovaries and Testes of Lytechinus Variegatus Lamarck (Echinodermata: Echinoidea)
Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
![Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase](/images/research/d91300a7-4d66-4d2c-90ac-293b0dbc5ff5/small/21048.jpg)
research Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase
Compound 15a was effective in inhibiting 5α-reductase.
research Glucose and Acetate Metabolism by Isolated Sheep Wool Follicles
Sheep wool follicles can metabolize both glucose and acetate using different pathways important for wool growth.
research Keratin-Mediated Hair Growth and Its Underlying Biological Mechanism
Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.
research Rodent Models in Placental Research: Implications for Fetal Origins of Adult Disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS
The method can measure vitamin B3 levels in human hair accurately.
research Specific Interpretation of Hair Concentrations in Two Fatal Metformin Intoxication Cases
Hair analysis showed very high metformin levels in two fatal overdose cases, suggesting it's useful in forensics but sweat may affect results.
research Hyperandrogenism, Elevated 17-Hydroxyprogesterone and Its Urinary Metabolites in a Young Woman with Ovarian Steroid Cell Tumor, Not Otherwise Specified: Case Report and Review of the Literature
A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.
research 11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
research External Lipid Function in Ethnic Hairs
African hair has the most lipids, while Caucasian hair is more hydrated and stronger.
research Experimental and Computational Approaches for Measuring Minoxidil Solubility in Propylene Glycol and Water Mixtures at Different Temperatures
Minoxidil dissolves better in propylene glycol and water as temperature and propylene glycol amount increase.
research Potential Applications of Topical Oxygen Therapy in Dermatology
Topical oxygen therapy may improve treatments for hair loss, acne, and chronic skin diseases with minimal side effects.
research Structural Changes of Hair Shaft After Application of Chemical Hair Straighteners: Clinical and Histopathological Study
Chemical hair straightening improves smoothness and shine but may cause side effects, suggesting a need for safer methods.
research Hair Growth Is Promoted by BeauTop via Expression of EGF and FGF-7
BeauTop helps hair grow by increasing certain growth factors.
research Analysis of Lipids in the Medulla of Japanese Hair and Their Function
Lipids in Japanese hair help maintain glossiness and structure.
research Omics for Precious Rare Biosamples: Characterization of Ancient Human Hair by a Proteomic Approach
The study developed a method to analyze ancient hair proteins using very small samples.
research Efficacy of Superficial Cryotherapy on the Eyebrows of Patients With Alopecia Universalis Also Treated With Contact Immunotherapy on the Scalp: A Prospective, Split-Face Comparative Study
Superficial cryotherapy significantly improves eyebrow hair growth in alopecia universalis patients.
research Evaluation of the 5α-Reductase Inhibitor Finasteride on Reproduction and Gonadal Development in Medaka, Oryzias Latipes
Finasteride negatively affects fish reproduction and gonadal development.
research LC-MS/MS Improves Screening Towards 21-Hydroxylase Deficiency
LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.
research Structural Characterization of Cyclosporin A, C, and Microbial Bio-Transformed Cyclosporin A Analog AM6 Using HPLC–ESI–Ion Trap-Mass Spectrometry
Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.
research Pharmacokinetics of Modified Slow-Release Oral Testosterone Over 9 Days in Normal Men With Experimental Hypogonadism
The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.
research Diphenyl Ethers as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
research Failure of Intercellular Adhesion in Hair Fibers Regarding Hair Condition and Strain Conditions
Hair breaks differently when wet or dry and is affected by its condition and treatments like perms and bleaching.
research PH Dependence of the Coiled-Coil Structure of Keratin Intermediate Filament in Human Hair by 13C NMR Spectroscopy and the Mechanism of Its Disruption
Keratin structure in hair is stable at pH 5-6 but disrupts between pH 6-7.
research Synthesis of 11α-Hydroxyprogesterone Haptens
Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.
research Recent Developments in Alopecias
Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.
research Non-Rhizobial Nodule Endophytes Improve Nodulation, Change Root Exudation Pattern and Promote the Growth of Lentil for Prospective Application in Fallow Soil
Certain bacteria can boost lentil growth and improve soil used for farming.