152 citations
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March 1988 in “Journal of The American Academy of Dermatology” In this study, a unique form of chronic superficial pyoderma gangrenosum with verrucous and ulcerative lesions was reported to heal without systemic corticosteroids in most patients.
3 citations
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October 2013 in “International Journal of Rheumatic Diseases” This case report found that a patient with cutaneous polyarteritis nodosa experienced rare and severe manifestations, including digital gangrene and a breast ulcer, requiring aggressive treatment and resulting in below-knee amputation.
12 citations
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May 2020 in “Dermatology and therapy” This case report describes a young woman with ankylosing spondylitis who developed a severe paradoxical skin reaction after six months on certolizumab, requiring treatment with secukinumab and methotrexate.
1 citations
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July 2025 in “Journal of Investigative Dermatology” July 2025 in “Journal of Investigative Dermatology” Upadacitinib effectively treats pyoderma gangrenosum.
October 2024 in “Dermatologica Sinica” This case report describes a 21-year-old male diagnosed with Crohn's disease and ulcerative pyoderma gangrenosum presenting with diverse extraintestinal symptoms, and highlights the success of a multi-drug treatment regimen including steroids and infliximab in improving clinical outcomes, though hematochezia was initially persistent.
October 2023 in “Nepal journal of dermatology, venereology & leprology” In this case report, researchers described a rare association of Pyoderma Gangrenosum with Neurofibromatosis, noting the occurrence of bone marrow suppression and acute Telogen Effluvium after treatment with Azathioprine, underlining the importance of monitoring for myelosuppression.
May 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports a case of pyoderma gangrenosum in a patient with rheumatoid arthritis, emphasizing the need to consider it as a differential diagnosis when ulcerative skin lesions resemble vasculitis.
1 citations
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September 2022 in “F1000Research” This case report describes a 56-year-old man with late-onset systemic lupus erythematosus where digital gangrene was an initial manifestation, highlighting its rarity as a primary sign.
This case report highlights the successful use of platelet-rich plasma infiltration to treat vasopressin-induced bilateral foot digit gangrene in a 20-year-old female, suggesting its potential in stimulating angiogenesis and wound healing, though further research is necessary to assess its general efficacy.
August 2022 in “F1000Research” This case report describes digital gangrene as a rare primary manifestation of late-onset systemic lupus erythematosus in a 56-year-old man, with marked lesion improvement following rituximab treatment.
1 citations
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July 2022 in “Indian Journal of Dermatology” This report describes the first documented case of bullous pyoderma gangrenosum developing on a cesarean section scar, which improved rapidly with oral prednisolone.
January 2024 in “Faculty of 1000 Research Ltd” This report describes a case of digital gangrene as an early manifestation of systemic lupus erythematosus in a 56-year-old man, highlighting it as a rare complication of late-onset SLE.
January 2022 in “Faculty of 1000 Research Ltd” This case report documents digital gangrene as an unusual early sign of late-onset systemic lupus erythematosus in a 56-year-old man, which improved with rituximab treatment.
5 citations
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January 2021 in “Inflammatory Bowel Diseases” In this report, a female patient with ulcerative colitis, alopecia areata, and pyoderma gangrenosum showed improvement in all three conditions after being treated with tofacitinib.
2 citations
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January 2014 in “Dermatology Online Journal” This article reviews hair-thread tourniquet syndrome, discussing its demographics, causes, and current treatment methods, but presents no new clinical findings.
March 2022 in “Journal of clinical case studies reviews & reports” COVID-19 can cause different skin issues, including rashes and hair loss.
November 2013 in “International Journal of Medical and Health Sciences” This review discusses hair tourniquet syndrome, highlighting its potential for delayed diagnosis and the association with maternal telogen effluvium, but reports no new clinical results.
October 1933 in “Experimental Biology and Medicine” In this study, subcutaneous injections of epinephrine in rats led to skin changes ranging from hair loss to necrosis, suggesting these effects were due to the epinephrine itself.
21 citations
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January 2022 in “Pharmaceutics” This systematic review investigated colchicine as a potential treatment for various skin conditions, finding that most studies reported generally positive clinical outcomes when used alone or with other drugs, despite some variability in results.
11 citations
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September 2021 in “Anais Brasileiros de Dermatologia” This article reviews how skin manifestations can aid in diagnosing various systemic diseases, focusing primarily on their association with rheumatologic conditions while also addressing vascular, granulomatous, and other disease impacts, aiming to provide dermatologists with practical diagnostic insights.
6 citations
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January 2013 in “Urology” This case report describes an 8-year-old child with penile tourniquet syndrome due to a constricting thread, which led to partial distal penile amputation and required surgical intervention.
January 2021 in “Springer eBooks” This chapter reviews skin manifestations in common rheumatic diseases, particularly those with polyarthritis, and offers a differential diagnosis of erythema nodosum without presenting new research findings.
41 citations
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June 2010 in “Clinics in Dermatology” This review discusses the negative effects of cigarette smoking on various skin conditions and emphasizes the importance of dermatologists advising patients to quit smoking, but it presents no new research findings.
40 citations
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July 2007 in “Dermatologic Therapy” This review discusses the pharmacologic properties, mechanisms, dosing options, and adverse effects of systemic glucocorticosteroids in dermatology, but reports no new findings.
35 citations
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August 2001 in “Journal of Cutaneous Medicine and Surgery” This paper reviews the use of tacrolimus for various conditions, noting its effectiveness in treating certain skin disorders but highlighting that some findings remain anecdotal due to limited case numbers.
26 citations
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October 2017 in “Clinical Reviews in Allergy & Immunology” This review explores skin manifestations associated with autoimmune liver diseases and highlights known and probable links, such as vitiligo's strong association with autoimmune hepatitis.
17 citations
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August 1983 in “Australasian Journal of Dermatology” The review says skin conditions with sterile pustules need more research for better treatments.
8 citations
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October 2022 in “Dermatology practical & conceptual” This source reports that tofacitinib and ruxolitinib showed potential efficacy and acceptable safety profiles in treating various autoimmune disorders, including alopecia areata and psoriasis, based on a review of clinical studies, while recommending physicians consider the individual risks and benefits.
5 citations
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October 2018 in “American Journal of Clinical Dermatology” This review discusses major dermatologic conditions occurring in the early post-hematopoietic stem cell transplant period and reports no new clinical results; it underscores dermatologists' role in recognizing critical complications.