March 2024 in “Cancer Research” This study found that eliminating senescent cells using senolytic drugs effectively prevented and reversed paclitaxel-induced peripheral neuropathy in mice.
March 2024 in “Frontiers in Endocrinology” In this study, a bidirectional Mendelian randomization analysis found a causal link between alopecia areata and hypothyroidism, indicating that each condition may influence the other, while no similar relationship was observed between androgenetic alopecia and hypothyroidism.
January 2024 in “Journal of Cosmetic Dermatology” This study reported that the 1565 nm non-ablative fractional laser treatment significantly improved various hair growth indices in patients with androgenetic alopecia compared to 5% minoxidil, demonstrating its superior clinical efficacy and safety for treating this condition.
January 2024 in “Journal of Biosciences and Medicines” In this study, combining Ginkgo biloba extract dropping pills with butylphthalide capsules improved cognitive and neurological function, daily living activities, and reduced inflammatory responses in patients with cognitive dysfunction following an acute ischemic stroke, compared to butylphthalide treatment alone.
This review discusses recent research on how sex hormones influence COVID-19 progression by affecting viral receptors, immune responses, and disease complications, and explores potential therapeutic uses based on clinical and assay studies.
December 2023 in “International Journal of Advanced Research in Science, Communication and Technology” This study evaluated an herbal shampoo's physicochemical properties and emphasized its safety, efficacy, and quality as a non-toxic natural hair care product.
November 2023 in “Biology” This study investigated m6A RNA modification in hair follicle development, finding that Hycole rabbits displayed longer hair, higher primary hair follicle ratios, and thicker skin compared to Rex rabbits, while also identifying key differential genes and pathways involved in hair growth.
November 2023 in “International Journal of Trichology” This case report describes a male child with alopecia areata and renal dysgenesis, highlighting a possible coincidental association that may require future genetic investigation.
October 2023 in “Cell & bioscience” This study identified a primitive coarse wool characteristic in Merino sheep that enhances environmental adaptability and fine wool yield without reducing quality, suggesting that epigenetic mechanisms, particularly involving the imprinted Gtl2-miRNAs locus, regulate this advantageous trait.
October 2023 in “Recent Trends in Pharmaceutical Sciences and Research” This review examines the anatomy and physiology of hair, focusing on the hair growth cycle and various types of alopecia, using animal models such as mice and rats to study the condition's pathophysiology and aid in developing new treatments.
August 2023 in “Fermentation” This review discusses the potential of metabolic engineering to enable sustainable industrial-scale production of L-aspartate and its derivatives, detailing current microbial production progress, limiting factors, and future prospects with emerging technologies in synthetic biology.
This study found that lentivirus-mediated overexpression of Sonic hedgehog significantly increased hair follicle stem cell proliferation and promoted hair follicle regeneration, with higher effects in non-alopecia areas.
This study found that an injectable calcium alginate-amelogenin hydrogel is biocompatible, degradable, anti-inflammatory, and promotes osteogenesis, which may enhance the bone healing process in jaw and facial bone defect areas by mediating the bone immune microenvironment.
March 2023 in “Cellular Molecular and Biomedical Reports” The researchers reported that lifestyle changes and medications significantly impact managing PCOS, highlighting the high prevalence of cardiovascular comorbidities and the common risk factor of high BMI in these patients.
February 2023 in “International journal of molecular sciences” This study used infrared spectral imaging to show for the first time the distribution of glypican-4 and glypican-6 in hair follicles across different growth phases, highlighting the potential of this technique for studying alopecia.
August 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated various herbal combinations for hair coloring and found that a formulation of Henna and Indigo provided a natural reddish-brown color with better retention compared to marketed herbal hair dyes, without using synthetic agents that can cause allergic reactions.
May 2022 in “Research Square (Research Square)” In this study, components like vitamin E, β-sitosterol, and linoleic acid in the kernel of Prunus mira Koehne were reported to promote hair growth in mice, possibly through the Wnt/β-catenin pathway.
March 2022 in “International Journal of Trichology” In this case report, a young female Indian patient with alopecia areata saw hair regrowth within 2 months of treatment with oral tofacitinib, with continued improvements over a 5-month period and no reported side effects.
January 2022 in “Faculty of 1000 Research Ltd” This study found that many participants in India lacked awareness and proper practices for home-based COVID-19 management, highlighting the need for targeted educational programs.
July 2020 in “Research Square (Research Square)” In this study, researchers found that girls aged 4-8 years with isolated premature thelarche had significantly advanced bone age, with obesity and elevated serum IGF-1 SDS and DHEAS SDS being key independent risk factors.
July 2020 in “Research Square (Research Square)” This study found that girls with isolated premature thelarche, confirmed by GnRH stimulation test, aged 4-8 years, may have significantly advanced bone age, with obesity and serum IGF-1 and DHEAS levels being key risk factors.
October 2019 in “International Journal of AYUSH Case Reports” This case study reported that a 29-year-old male patient with alopecia areata patchy experienced hair regrowth and relief from scalp itching and dandruff after using medicinal leech therapy and specific internal medicines for three months.
July 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that Indian women with PCOS had distinct gut microbiome profiles, linking specific bacterial genera to metabolic and hormonal predictors of the condition.
April 2019 in “Journal of Investigative Dermatology” In this pilot study, combined platelet-rich plasma therapies showed potential benefits for improving skin elasticity and vascular network density in morphea patients, but the small sample size limits definitive conclusions.
April 2018 in “Journal of Investigative Dermatology” In this study using a transgenic mouse model, Id2 overexpression in hair follicle stem cells prolonged quiescence by affecting gene expression, partly independent from BMP signaling.
This study found that 6-Gingerol significantly suppressed hair growth in mice by interfering with the hair cycle and altering growth factor concentrations.
January 2015 in “Journal of evolution of medical and dental sciences” In this study, topical tacrolimus 0.03% cream showed good to excellent response in treating alopecia areata in 70% of participants, with no cutaneous or systemic side effects observed.
August 2014 in “Chinese Journal of Dermatology” This study found that scalp psoriasis in China commonly affects the forehead hairline, is worsened by seasonal changes, and often negatively impacts patients' quality of life.
January 2013 in “Psychiatry and clinical neurosciences” This case report emphasizes the importance of investigating physical symptoms in patients with depression, as persistent loss of libido in this patient led to the diagnosis of craniopharyngioma.
December 2007 in “한국미용학회지” This study found that a complex oriental medicine extract applied topically promoted hair regrowth in mice with alopecia at a similar rate to 3% minoxidil.