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Not having the gene PLAAT3 leads to fat loss, high insulin resistance, and abnormal fat levels in the blood due to a disruption in fat cell development and function.

Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.

PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.

Innate lymphoid cells type 1 may contribute to alopecia areata.

IL-17 and certain immune cells are linked to more severe alopecia areata.

The humanized AA mouse model is better for testing new alopecia areata treatments.

Lichen Planopilaris is a hair loss condition best treated early with various medications, including hydroxychloroquine, to prevent permanent baldness.

Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.

Different types of stem cells in the skin contribute to the variety of melanoma forms.

A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.

N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.

Crataegi Fructus water extract helps hair grow better and thicker.

Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.

Yikgeebohyul-tang promotes hair growth and could help treat hair loss.

TGFβ signaling prevents sebaceous gland cells from producing fats.

Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.

Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.

The document suggests a rare skin condition might be caused by a genetic phenomenon.

Liquid nitrogen spray caused a temporary, harmless swelling under the skin in an elderly woman.

Oral tofacitinib helped regrow hair in over half of the patients with severe alopecia, but relapses and side effects were common.

A hair tightly wrapped around a toddler's toe caused severe crying and was treated by surgery.

Janus kinase inhibitors show promise in treating alopecia areata but need more safety research.

Photodynamic therapy may not work for erythroplasia of Queyrat and could lead to invasive squamous cell carcinoma.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.

Finasteride doesn't affect sleep spindles in men.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

Tofacitinib is a potential alternative treatment for alopecia totalis, especially in patients with a shorter duration of the condition and more preserved hair follicles, but the overall response rate is low.