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Blocking YAP/TAZ could be a new way to treat skin cancer.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Nanoparticle-based herbal remedies could be promising for treating hair loss with fewer side effects and lower cost, but more research is needed.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

CD4+ skin cells may be precursors to basal cell carcinoma.

Immunomodulatory therapies are effective for treating cutaneous lymphoma, particularly in early stages.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Hair follicles can be used to quickly assess drug effects in cancer treatment.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.