research Inflammatory Loops in the Epithelial-Immune Microenvironment of the Skin and Skin Appendages in Chronic Inflammatory Diseases
Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.
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180-210 / 465 results research Phenotypic Analysis of T-Cells in Extensive Alopecia Areata Scalp Suggests Partial Tolerance
T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.
research Janus Kinase Inhibitor Increases Hair Growth by Increasing Beta-Catenin Activity in Outer Root Sheath Cells
JAK inhibitors help hair growth by boosting beta-catenin activity in hair root cells.
research Expression of Peroxisome Proliferator Activated Receptors (PPARs) in Human Hair Follicles and PPARα Involvement in Hair Growth
PPAR alpha may help in hair growth and could be a target for treatment.
research T-Cell Induced-Self MHC Class I/Peptide Complexes May Enable De Novo Tolerance Induction to Neo-Antigens Occurring Outside of the Thymus
Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.
research Loss of Epidermal PLCγ1 Induced Sebaceous Gland Hyperplasia and Sparse Hair
Removing PLCg1 from skin cells caused thicker oil glands and less hair in mice.
research A New Target for Squamous Cell Skin Cancer?
Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.
research Acquired Constriction Ring Syndrome as a Cause of Inconsolable Crying in a Child: A Case Report
A hair tightly wrapped around a toddler's toe caused severe crying and was treated by surgery.
research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
research Investigating the Effects of Metabolic Dysregulation on Hair Follicles: A Comparison of HIV-Infected Women With and Without Central Lipohypertrophy
Central lipohypertrophy in HIV-infected women may lead to shorter eyelashes.
research Genetic Dissection of Retinoic Acid Function in Epidermis Physiology
Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.
research The New Approach to Early Diagnosis of Adenomyosis
A new method can almost perfectly distinguish adenomyosis from similar conditions using blood tests.
research Assessing the Safety of Topical Minoxidil Through Disproportionality Analysis of FAERS Reports
Topical minoxidil may cause more side effects than currently listed, needing updated safety information.
research Management of Difficult Infections in Systemic Lupus Erythematosus
Managing severe infections in SLE patients requires tailored treatment strategies.
research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
research Microscopic Polyangiitis Secondary to Mycobacterium Abscessus in a Patient with Bronchiectasis: A Case Report
A 70-year-old woman with bronchiectasis developed a rare immune disease due to a bacterial infection, requiring a difficult balance of treatments.
research Frontal Fibrosing Alopecia: An Example of Disrupted Aryl Hydrocarbon Receptor-Mediated Immunological Homeostasis in the Skin?
Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.
research Topical Minoxidil Therapy for Androgenetic Alopecia
Topical minoxidil may not improve the appearance of balding men, according to a letter in this document.
research Mitochondrial DNA Damage, Oxidative Stress, And Atherosclerosis
Improving mitochondrial health may better treat atherosclerosis than antioxidants.
research Adipose-Derived Stem Cell Secretome and Its Potential Role in the Treatment of Androgenetic Alopecia
Adipose-derived stem cells may help treat hair loss.
research Plasma-Polymerized Antibacterial Coating of Ovine Tendon Collagen Type I Crosslinked with Genipin and Dehydrothermal-Crosslinked as a Cutaneous Substitute for Wound Healing
The GNP crosslinked scaffold with antibacterial coating is effective for rapid wound healing and infection prevention.
research Risk Factors and Comorbidities Associated With Central Centrifugal Cicatricial Alopecia
Certain hairstyles, diabetes, scalp infections, and vitamin D deficiency may increase the risk of hair loss in Black women; more research is needed for better treatment.
research Baricitinib for the Treatment of Moderate-To-Severe Alopecia Areata
Baricitinib helps regrow hair in severe alopecia areata and is safe, but more research is needed.
research Formulation and Evaluation of Hair Growth Enhancing Effects of Oleogels Made from Rosemary and Cedarwood Oils
Oleogels made from Cedarwood and Rosemary oils can enhance hair growth, but combining both oils doesn't increase the effect.
research Conceptual Basis for Use of Chemotherapeutic Agents and Their Pharmacology
The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.
research The Use of Keratin Biomaterials Derived from Human Hair for the Promotion of Rapid Regeneration of Peripheral Nerves
Keratin from human hair helps nerves heal faster.
research Interleukin-15 Is a Hair Follicle Immune Privilege Guardian
Interleukin-15 can help hair growth and protect hair follicles.
research Azathioprine-Induced Severe Myelosuppression Accompanied by Massive Hair Loss and Painful Oral Ulcer in an Autoimmune Hepatitis Patient with NUDT15 Minor Variant: A Case Report
Genetic testing is crucial before giving azathioprine to avoid severe side effects.
research The Role of Candidate Pharmacogenetic Variants in Determining Valproic Acid Efficacy, Toxicity, and Concentrations in Patients with Epilepsy
Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.
research Acquired Trichomegaly with Topiramate
A woman's eyelashes grew thicker and longer after taking topiramate, but returned to normal when she stopped the medication.