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Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Agmatine may help reduce seizures linked to hormone changes in female rats.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Neurosteroids show promise for treating epilepsy and more research is needed.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Finasteride can cause sexual problems and depression in young men.

Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.

Gut microbes significantly affect brain steroid levels.

Adrenal disorders can cause lasting brain and behavior issues in children.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.

The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.

Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.

Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.

Flavonoids in Iraqi marshland plants have potential health benefits like antioxidant and anti-inflammatory effects.

Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.