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Many pediatric epilepsy patients experience preventable severe adverse drug reactions, especially with certain medications and risk factors.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Ashwagandha root improved symptoms of nonclassic 11-hydroxylase deficiency in an elderly woman.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Meis2 is essential for touch sensation and nerve function in mice.

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.

Finasteride reduces movement issues in Parkinson's disease rats.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Cannabinoids may help treat various skin conditions.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Finasteride reduces new brain cells in male mice, possibly causing depression.

H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.

Recreational drug use can cause misdiagnosed conditions and drug interactions in HIV patients.

A person with Turner Syndrome showed severe schizophrenia that didn't respond to treatment and had brain shrinkage.

Impulsiveness is common across various psychiatric disorders and linked to many psychological symptoms.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

Treatment during development affects hormone balance and sexual behavior in male rats.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.