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The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Some systemic treatments work for nail psoriasis but can have serious side effects.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Apoptosis is crucial for healthy skin and treating skin diseases.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.

Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Prolactin may be important for skin growth and immune function.

A woman's total hair loss from hepatitis C treatment grew back after stopping the medication.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

Nanoparticles with more oleic acid improved the delivery and stability of the drug spironolactone.

EVG staining is a valuable, simple, and cost-effective method for diagnosing various skin conditions in dermatopathology.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

Itraconazole was effective in treating unusual M. canis infections in only one of two HIV-infected men.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.