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New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

Sweat gland development involves two unique skin cell programs and a temporary skin environment.

Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Lipase H is important for hair follicle function and shaping hair fibers.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Stress can stop hair growth in mice, and treatments can reverse this effect.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

The effects of estrogen on human scalp hair growth are unclear and need more research.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.