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The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Omega-6 fats in certain cells boost male hormone production.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

sPLA2-X is crucial for normal hair growth and follicle health.

Cannabidiol shows promise as an effective treatment for acne.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Researchers found four genes that could help diagnose severe alopecia areata early.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

The research suggests that Tourette syndrome is linked to both brain signaling and immune system pathways.

Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

Using neurohormones to control keratin can lead to new skin disease treatments.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.

Blocking adenosine A2B receptor may prevent or treat hearing loss.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.