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This research found that the transfer reaction catalyzed by human plasma and guinea pig hair follicle transglutaminases aligns with a ping-pong mechanism involving peptide-bound glutamine.

This guide provides an overview of the complex roles and mechanisms of various receptors and channels in pharmacology but does not report new experimental results.

This review highlights the traditional medicinal uses, phytochemical composition, and pharmacological properties of Musa paradisiaca, noting its applications in treating diarrhea and other conditions, and identifying key bioactive compounds with antimicrobial, antioxidant, and other bioactivities through in vitro and in vivo studies.

This review discusses the design and advances of lipid–polymer hybrid nanoparticles as promising delivery systems for genome editing strategies, highlighting their potential in biomedical applications.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

This study found that glucose starvation and hypoxia are physiological triggers of ER stress in in vitro differentiated adipocytes, rather than high concentrations of saturated fatty acids, cholesterol, or proinflammatory cytokines.

This review highlights how advanced nanocarrier and microneedle-based transdermal drug delivery strategies can potentially improve the treatment of skin diseases by enhancing site-specific drug delivery, increasing skin penetration, and reducing systemic toxicity compared to conventional methods.

This pilot study found that hair metabolome analysis may help differentiate pregnancy complications from healthy pregnancies by revealing significant metabolite differences between trimesters.

This review discusses recent advances in using nanocarrier-loaded gels for various medical applications and reports no new clinical results, highlighting potential advantages in therapeutic strategies.

This review highlights the potential of wedelolactone from the plant Wedelia Chinensis, summarizing its reported pharmacological effects, including anti-inflammatory, antiviral, antibacterial, antitumor, anti-osteoporosis activities, and organ protection based on existing in vitro and in vivo research findings.

This review highlights the emerging role of long non-coding RNAs (lncRNAs) in dermatology, suggesting that lncRNAs significantly impact signaling pathways involved in normal skin functions and skin diseases, offering potential as biomarkers and therapeutic targets.

This study found that untargeted hair metabolomics analysis detected significantly altered endogenous biomolecules, potentially serving as biomarkers for identifying oxidative cosmetic hair treatments like bleaching.

This abstract provides a comprehensive overview of enzyme classification, function, and interaction with drugs, but does not present new research findings.

This review discusses the integration of biodegradable biomaterials with drugs and stem cells for diabetic wound repair, but reports no new clinical results and highlights the need for further translation to clinical practice.

This article reviews CRISPR/Cas system delivery methods for genome editing and highlights RNA's promise in non-viral in vivo applications but reports no new clinical results.

This paper critically reviews recent advances in the use of keratin-based biomaterials, highlighting their potential applications in wound healing, drug delivery, and tissue regeneration due to their biocompatibility, biodegradability, and ability to support cell growth.

This review analyzes the role of silver nanoparticles in wound healing, highlighting their antimicrobial, anti-inflammatory, and tissue-regenerating properties, and emphasizes the need for further research to optimize formulations and ensure safety.

This study found that exogenous glutamic acid can promote hair growth and keratinocyte proliferation, suggesting a novel signalling pathway in the skin.

This study reported that in animal studies of androgenetic alopecia, a biodegradable microneedle patch releasing glutamic acid promoted hair regeneration more effectively than daily minoxidil, with higher hair follicle counts and less frequent dosing, showing the potential for clinical application.

This study found that exogenous glutamic acid promoted hair growth and keratinocyte proliferation, indicating a potential new signaling pathway in the skin.

This study suggests that the hydrogel nanoparticle formulation of hair growth-promoting compounds may enhance hair follicle penetration and induce hair growth in tested models, demonstrating its potential as a hair growth treatment.

This study found that the developed hydrogel nanoparticles showed potential for enhancing hair growth by effectively delivering and releasing hair growth-promoting herbal extracts into hair follicles.

Poly-γ-glutamic acid may help reduce hair loss.

This study found that ultra-high molecular weight poly-γ-glutamic acid promoted hair growth in telogenic C57BL/6 mice by inhibiting 5-alpha reductase activity and inducing the anagen phase.

This study suggests that hair-follicle afferent axons can be presynaptically inhibited by boutons containing the enzyme glutamic acid decarboxylase, which is linked to the synthesis of γ-aminobutyric acid.

This study found that altered amino acid metabolism, specifically involving glutamic and aspartic acids, promotes neurovascular reactivity in rosacea, suggesting a potential metabolic target for treatment.

This study found that ferulic acid significantly reduced seizure susceptibility and depression-like behaviors in a mouse model of catamenial epilepsy, likely by restoring hormone levels and neurotransmitter activity.

Hair amino acid levels can indicate metabolic disorders.

This study reviewed preclinical evidence suggesting that topical glutamic acid can enhance hair regrowth and skin healing in burn-induced alopecia, highlighting its potential as a simple, low-cost treatment option that warrants further clinical trials.

This study reports that a 190,000 molecular weight protein, identified as trichohyalin, may play a matrix role in the development of inner root sheaths in hair follicles.