research Carrier-Free Injectable Hydrogel Self-Assembled Using Natural Thymol and Glycyrrhizin for MRSA-Infected Wound Healing in Rats
The new hydrogel made from thymol and glycyrrhizin helps heal MRSA-infected wounds in rats effectively.
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research Polymeric Nanohydrogel in Topical Drug Delivery System
Polymeric nanohydrogels show potential for skin drug delivery but have concerns like toxicity and regulatory hurdles.
research Research Progress of Extracellular Vesicles-Loaded Microneedle Technology
Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.
research Nanocarriers for Melatonin Delivery
Nanocarriers make melatonin more effective and reduce side effects.
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
research From Plants to Wound Dressing and Transdermal Delivery of Bioactive Compounds
Plant-based compounds can improve wound dressings and skin medication delivery.
research Sensitive Quantitative In Vivo Assay for Evaluating the Effects of Biomolecules on Hair Growth and Coloring Using Direct Microinjections into Mouse Whisker Follicles
The new "whisker follicle microinjection assay" can test how different biomolecules affect hair growth and color.
research The Medicinal Activity of Lyophilized Aqueous Seed Extract of Lepidium Sativum L. in an Androgenic Alopecia Model
The seed extract of Lepidium sativum L. can potentially treat hair loss, showing effects similar to 5% minoxidil.
research Synchronous Fluorescence as a Green and Selective Method for the Simultaneous Determination of Finasteride and Tadalafil in Dosage Form and Spiked Human Plasma
A new green method accurately measures finasteride and tadalafil in drugs and plasma.
research Efficacy, Tolerability, and Superiority of Propylene Glycol-Free, North American Witch-Hazel-Based Solution of 5% Minoxidil Sulfate for the Treatment of Female Androgenetic Alopecia
A witch-hazel-based 5% minoxidil solution is effective and safe for women with hair loss who didn't respond to regular minoxidil, especially if they're sensitive to propylene glycol.
research Liquid Chromatography-Mass Spectrometry Based Isotopic Abundance Ratio Analysis of the Consciousness Energy Healing Treated L-Cysteine
Energy healing treatment improved L-cysteine's stability, solubility, bioavailability, and shelf-life.
research KY19382, A Novel Activator of Wnt/β-Catenin Signaling, Promotes Hair Regrowth and Hair Follicle Neogenesis
KY19382 helps to regrow hair and create new hair follicles.
research Compliance to Topical Minoxidil and Reasons for Discontinuation Among Patients With Androgenetic Alopecia
Most patients stop using topical minoxidil due to side effects.
research Hair Regrowth Boosting Via Minoxidil Cubosomes: Formulation Development, In Vivo Hair Regrowth Evaluation, Histopathological Examination, and Confocal Laser Microscopy Imaging
A new version of minoxidil, a hair loss treatment, was made using nanotechnology. This version, called minoxidil cubosomes, works better and causes fewer skin reactions than the old version. It also penetrates and stays in the skin better, promoting hair regrowth. It's safe and could be a good alternative to current treatments.
research Latanoprost-Loaded Nanotransfersomes Designed For Scalp Administration Enhance Keratinocytes Proliferation
Latanoprost-loaded nanotransfersomes could help treat hair loss by promoting hair growth.
research Methods of Treatment for Patients with Androgenetic Alopecia Based on the Department of Dermatology in Cracow
The most common treatment for hair loss in the study was a 5% minoxidil solution, with women more likely to receive multiple medications. A significant number of patients also had hypothyroidism.
research Sex-Specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids
Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
research Deoxycorticosterone’s Anticonvulsant Effects in Infant Rats Are Blocked by Finasteride, but Not by Indomethacin
Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
research Disruption of P2RY5, an Orphan G Protein–Coupled Receptor, Underlies Autosomal Recessive Woolly Hair
Mutations in the P2RY5 gene cause autosomal recessive woolly hair.
research LPA3, A Unique G Protein-Coupled Receptor For Lysophosphatidic Acid
LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.
research Metabolic Effect at Six and Twelve Months of Cyproterone Acetate (2 mg) Combined with Ethinyl Estradiol (35 µg) in 31 Patients
The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.
research Differential Expression of a Gene Homologous to a G-Alpha Protein Gene in Neonatal Mouse Skin During Development of Hair Follicles
The G(S) alpha subunit gene may help start hair follicle growth in newborn mice.
research Valproate, Acetylcarnitine, Folic Acid, and Vitamin B12 in Spinal Muscular Atrophy: Preliminary Data of an Open-Label Study in Children
The treatment with valproate, acetylcarnitine, folic acid, and vitamin B12 may improve muscle strength in children with SMA without significant side effects.
research Evaluation of the Relationship Between Serum G Protein-Coupled Estrogen Receptors (GPER-1) Levels and the Severity and Duration of the Disease in Patients with Androgenetic Alopecia: A Case-Control Study
Higher GPER-1 levels are linked to more severe and shorter-duration androgenetic alopecia, suggesting GPER-1 as a potential treatment target.
research The G-Protein Coupled Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
research Oculoplastic Surgery Atlas: Eyelid Disorders
Surgical excision is the best treatment for SCC, but intralesional cidofovir might be a viable alternative.
research G-Proteins, Receptor Signal Transduction, and Growth Hormone Secretion
The document concludes that antiandrogenic drugs like cyproterone acetate and spironolactone are effective but not permanent treatments for skin-related androgenization in women.
research Evaluation of Serum G Protein-Coupled Estrogen Receptor 1 (GPER-1) Levels in Patients with Androgenetic Alopecia
Alopecia patients have less GPER-1, which might affect hair loss.
research Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp
Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.
research The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia
E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.