23 citations,
July 2003 in “Pharmacology, Biochemistry and Behavior” Finasteride blocks progesterone's effect on absence seizures in rats.
21 citations,
June 2005 in “Alcoholism: Clinical and Experimental Research” Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.
17 citations,
November 2014 in “American Journal of Physiology-gastrointestinal and Liver Physiology” Finasteride helps brain function in rats with liver-related brain issues.
13 citations,
January 2020 in “Neuroscience” Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
12 citations,
March 2018 in “Analytical chemistry” Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.
10 citations,
February 2015 in “Journal of Pharmaceutical and Biomedical Analysis” Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
7 citations,
January 2003 in “Elsevier eBooks” Testosterone is crucial for development, growth, and various body functions in mammals.
5 citations,
February 2010 in “Drug development and industrial pharmacy” Vesicles made of behenyltrimethylammonium chloride and stearic acid can triple the skin absorption of hinokitiol, which may help with hair growth.
4 citations,
January 2013 in “Dissolution Technologies” A method was developed to test the breakdown of Finasteride capsules, showing it can tell the difference between different brands and highlighting the need for standard tests and ingredient consistency.
October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.
January 2017 in “Elsevier eBooks” Stress and hormones like progesterone can affect absence seizures, but their effects change with different life stages.
421 citations,
January 2015 in “Chemical Society Reviews” Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.
77 citations,
March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
77 citations,
July 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
68 citations,
March 2019 in “Advanced Healthcare Materials” Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
67 citations,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
67 citations,
June 2018 in “Engineering in Life Sciences” Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.
62 citations,
December 2013 in “Aaps Journal” Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.
61 citations,
June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” Cationic polymers improved liposome stability and increased skin absorption of aciclovir and minoxidil.
61 citations,
September 2008 in “Biological & Pharmaceutical Bulletin” Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.
60 citations,
January 2014 in “Anais Brasileiros De Dermatologia” Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
58 citations,
December 2012 in “Aaps Pharmscitech” LCN may improve finasteride delivery for hair loss treatment.
57 citations,
June 2021 in “Polymers” Photothermal hydrogels are promising for infection control and tissue repair, and combining them with other treatments could improve results and lower costs.
57 citations,
September 2017 in “Journal of controlled release” Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.
48 citations,
September 2017 in “Frontiers in Bioscience” Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
47 citations,
August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
46 citations,
September 2014 in “Steroids” Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
43 citations,
February 2020 in “Clinica chimica acta” Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
40 citations,
December 2019 in “Neurobiology of Stress” Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
36 citations,
August 2011 in “Journal of Controlled Release” Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.