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This study reports that the β-catenin inhibitor tegatrabetan reduced hair growth and hair follicle numbers in mice, suggesting its potential as a model for developing new hair growth materials.

In this study, human umbilical cord mesenchymal stem cell-derived exosomes were found to promote the growth of human hair dermal papilla cells, partly by enhancing AKT-dependent signaling pathways, suggesting a potential role in treating hair loss.

The study found that safflower extract may help protect human follicle dermal papilla cells from cisplatin-induced damage, suggesting its potential as an adjuvant in chemotherapy to mitigate hair follicle cell damage.

In this study, stress hormone CRF was found to inhibit hair growth, suggesting that the HPA axis is functional in human dermal papilla cells and contributes to hair loss under stress conditions.

This study showed that the stress hormone CRF inhibits hair growth and induces hair loss by affecting both the proliferation of human dermal papilla cells and hair follicle function.

This study suggests that FGF18 may enhance radioresistance in telogen hair follicles by inducing cell cycle arrest, potentially serving as a radioprotector against radiation-induced hair follicle damage.

This study found that bursts of ERK activation in the epidermis of mice were linked to cell division, supporting synchronized cell proliferation and transient ERK activity in living tissues.

This study found that overexpression of antizyme in mice with activated MEK reduced skin tumor growth by inhibiting putrescine accumulation, slowing cell growth, and increasing G2/M transit time.

This study found that the ethanolic extract of Acanthus ebracteatus demonstrated potential as an anti-hair loss treatment by promoting dermal papilla cell proliferation, inhibiting 5α-reductase activity, and reducing inflammation in vitro.

HA-iMSC-EVs can improve skin aging by boosting cell growth and restoring collagen and elastin.

This study found that the herbal extract HX109 promoted hair growth in mice by increasing cell viability and enhancing hair regrowth, with the effects increasing as doses rose.

This case study details a 31-year-old woman diagnosed with secondary syphilis that presented with chronic headaches and hair loss, ultimately attributed to neurosyphilis and alopecia syphilitica.

This study is the first to describe a mixed pattern of essential syphilitic alopecia using trichoscopy, identifying features like tapered bended hairs and perifollicular hyperkeratosis in a patient without secondary syphilis symptoms.

This report details a rare case of late latent syphilis in a 17-year-old male with unusual symptoms like polyarthritis and hair loss, which resolved following antibiotic treatment, highlighting varied syphilis presentations and the importance of STI screening, especially in high-risk groups.

In this study, zinc supplementation at 2.00 g/camel/day improved hair growth in lactating camels but did not affect milk production, while for calves, doses of 0.50–0.75 g/camel/day enhanced growth and hair development.

This study found that DHT treatment led to reduced cell growth, increased cell death, cell cycle arrest, ROS production, and senescence in normal human dermal papilla cells, potentially mediated by altered miRNA expression.

In this study, homeopathic Radium bromatum showed potential anti-cancer effects against human lung and liver cancer cells in vitro while exhibiting low cytotoxicity towards non-cancerous kidney cells.

This study presents a new classification of adult human scalp hair patterns based on high-resolution photographs, which may assist hair restoration surgeons and dermatologists in determining appropriate punch size for follicular unit extraction.

This updated guideline from the Endocrine Society highlights the importance of endocrinologists in providing safe and effective hormone regimens for gender-affirming care, especially for adolescents who have entered puberty.

This study found that epidermal growth factor significantly enhances the proliferation of hair follicle-derived mesenchymal stem cells through the EGFR/ERK and AKT pathways, without involving the STAT3 pathway.

This study reported that adipose-derived stem cell-conditioned medium demonstrated anti-tumorigenic effects on B16 melanoma cells both in vitro and in vivo, indicating potential for future melanoma treatment.

This study found that de-saponinated Camellia seed cake extract promotes hair growth in vitro and in vivo by enhancing dermal papilla cell proliferation and modulating signaling pathways and growth factor expression.

This study found that microneedling with growth factors improved collagen production and connective tissue reorganization more than microneedling with saline in facial rejuvenation.

This review reports that the compound Cepharanthine shows promise as a cancer therapy by inducing cell death, arresting cell growth, inhibiting tumor progression, modulating key oncogenic pathways, and reversing multidrug resistance, suggesting its potential for further investigation in oncology.

This study found that exosomes derived from human umbilical cord mesenchymal stem cells enhanced the growth of human hair dermal papilla cells by promoting cell cycle progression and activating PI3K and Akt-dependent pathways, indicating potential for hair loss treatment.

Human epidermal stem cells divide faster than previously thought.

This study found that cPPARγ and dnPPARγ isoforms are differentially expressed in healthy human skin, suggesting that PPARγ modulators may have compartment-specific effects depending on isoform presence.

This study found that fermented mackerel oil increased hair growth by promoting dermal papilla cell proliferation and cell cycle progression through wnt/β-catenin signaling activation in vibrissa follicles.

This study found that doxorubicin-induced oxidative stress downregulates FLIPs and phosphorylates EF2, sensitizing prostate cancer cells to TRAIL; antioxidants may reduce doxorubicin's effectiveness, warranting further investigation.

This study suggests that skin-derived precursors from Sox2(+) hair follicle dermal cells have the potential to function as dermal stem cells, supporting hair morphogenesis, dermal maintenance, and wound-healing.