research TRAIL Sensitization of PC3 Prostate Cancer Cells by Doxorubicin Can Be Blocked by the Antioxidant N-Acetyl-Cysteine or by the Iron Chelator Deferoxamine
Antioxidants can block the cancer-fighting effects of doxorubicin.
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research Canonical and Dominant Negative Peroxisome Proliferator-Activated Receptor Gamma Isoforms Are Differentially Expressed in Human Skin and Skin Appendages
Different types of PPARγ are found in varying amounts in human skin and its parts, which could affect how skin treatments work.
research In Silico Prediction of Prostaglandin D2 Synthase Inhibitors from Herbal Constituents for the Treatment of Hair Loss
Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.
research Evaluation of the Efficacy of Transdermal Drug Delivery of Calcipotriol Plus Betamethasone Versus Tacrolimus in the Treatment of Vitiligo
Calcipotriol plus betamethasone with microneedling works better than tacrolimus for treating vitiligo.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
research Intracrine Testosterone Activation in Human Pancreatic Beta-Cells Stimulates Insulin Secretion
Testosterone helps human pancreatic cells increase insulin release.
research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Regeneration After Facial Nerve Injury
Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
research The Impact of Potential Pill Splitting on Generic and Branded Finasteride Uptake
Pill splitting increased generic finasteride sales but didn't affect branded finasteride sales.
research Use of Call Center Methodology to Collect Quality of Life Data in a Clinical Trial: A Case Study of Patients with Diabetic Macular Edema
Using a call center to collect data in a trial for eye disease in diabetics led to high response rates and very little missing information.
research Time Lags Between Various Maturity Measures and Spermarche
Certain maturity signs appear before and after the first release of sperm in boys.
research Economic Analysis of Cataract Surgery in Europe: An Analysis of Hospital Databases Available in 11 Countries
Cataract surgery in Europe varies in frequency and cost between countries.
research Prevalence and Some Risk Factors with Therapeutic Trial of Sheep Dermatophytosis in Egypt
Tioconazole cream is highly effective and easy to use for treating sheep dermatophytosis.
research Hydrobiome Of Thermal Waters: Potential Use In Dermocosmetics
Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.
research Outcome and Clinical-Biological Characteristics of Patients with Advanced Breast Cancer Undergoing Removal of Ovarian/Pelvic Metastases
Patients with advanced breast cancer and high hormone receptor levels who had surgery for ovarian/pelvic metastases lived longer, especially if they had high estrogen receptor levels.
research Treatment of Recurrent Priapism in Sickle Cell Anemia With Finasteride: A New Approach
Finasteride helps reduce priapism in sickle cell anemia patients.
research Proteomic Analysis Identifies Differentially Expressed Proteins Participating in Forming Type III Brush Hair in Yangtze River Delta White Goat
Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.
research Skin Disorders in Overweight and Obese Patients and Their Relationship With Insulin
Obesity is linked to skin conditions like acanthosis nigricans and skin tags, which may indicate high insulin levels.
research Peroxisome Proliferator Activated Receptor-Gamma Tissue Expression and Gene Polymorphism in Alopecia Areata in an Egyptian Sample
PPAR-γ may be a key target for treating alopecia areata and other skin conditions.
research Experimental Aspects Concerning the Laser Action on Living Tissue
Low energy laser therapy effectively treats certain skin conditions and improves recovery time without side effects.
research Worldwide Review of Restrictions Placed Upon People With HIV/AIDS
The review concluded that restrictions on people with HIV/AIDS often violated their rights without proven effectiveness in stopping the virus, highlighting education as the best control method.
research Ethnicity, Obesity, and the Prevalence of Impaired Glucose Tolerance and Type 2 Diabetes in PCOS: A Systematic Review and Meta-Regression
Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.
research Protoporphyrin IX: The Good, the Bad, and the Ugly
Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
research Trichoscopy for Common Hair Loss Diseases: Algorithmic Method for Diagnosis
The conclusion is that an algorithm using trichoscopy helps diagnose different types of hair loss but may need updates and a biopsy if results are unclear.
research Dr. Shoji Okuda (1886-1962): The Great Pioneer of Punch Graft Hair Transplantation
Dr. Shoji Okuda was a pioneer in hair transplant surgery, but his work was initially overlooked and is now recognized alongside Dr. Norman Orentreich.
research Pigmented Contact Dermatitis Due to Therapeutic Sensitizer as a Complication of Contact Immunotherapy in Alopecia Areata
Some patients with severe alopecia areata developed skin darkening from their treatment, which may indicate a less effective response to the therapy.
research Acute Dermal and Ocular Irritation Testing of Rice Bran Supercritical CO2 Extract (RB-SCE) and 0.5% RB-SCE Essence Product
Rice bran extract caused moderate skin irritation but no eye irritation, while a diluted essence was not irritating to skin and only slightly to guinea pigs.
research Sex Hormone-Binding Globulin as an Early Biomarker and Therapeutic Target in Polycystic Ovary Syndrome
SHBG may be a useful early indicator and treatment target for PCOS.
research Significance of Dermoscopy in Acute Diffuse and Total Alopecia of the Female Scalp: Review of Twenty Cases
Dermoscopy effectively distinguishes between acute total hair loss and other types of female hair loss.
research Differential Expression and Functionality of ATP-Binding Cassette Transporters in the Human Hair Follicle
Certain transporters are found in human hair follicles and may affect hair growth and loss.
research Topical Estrogen Therapy for Androgenetic Alopecia in Menopausal Females
Topical estrogen helps hair growth in menopausal women with no major side effects.