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    Research 30 of 35

    1. A model for the turnover of dihydrotestosterone in the presence of the irreversible 5α-reductase inhibitors GI198745 and finasteride Clinical Pharmacology & Therapeutics · 1998 · 60 citations
    2. Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone. Biochemical Pharmacology · 2001 · 22 citations
    3. Androgenetic Alopecia: Overview Journal of Cutaneous Medicine and Surgery · 1999 · 3 citations
    4. Dihydrotestosterone and the Concept of 5α–Reductase Inhibition in Human Benign Prostatic Hyperplasia European Urology · 2000 · 184 citations
    5. Novel agents for the treatment of alopecia Seminars in Cutaneous Medicine and Surgery · 1998 · 29 citations
    6. Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives 2002 · 233 citations
    7. Adverse Side Effects of 5α‐Reductase Inhibitors Therapy: Persistent Diminished Libido and Erectile Dysfunction and Depression in a Subset of Patients The Journal of Sexual Medicine · 2010 · 223 citations
    8. Hormonal Therapy for Acne Seminars in Cutaneous Medicine and Surgery · 2008 · 96 citations
    9. Idiopathic Hirsutism* Endocrine Reviews · 2000 · 47 citations
    10. Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility1 Biology of Reproduction · 2004 · 35 citations
    11. The Effect of 5 -Reductase Inhibitors on Erectile Function International Journal of Andrology · 2008 · 31 citations
    12. ANDROGENETIC ALOPECIA Dermatologic Clinics · 2000 · 30 citations
    13. Incomplete Recovery of Erectile Function in Rat after Discontinuation of Dual 5‐Alpha Reductase Inhibitor Therapy The Journal of Sexual Medicine · 2012 · 29 citations
    14. Estimating the Contribution of the Prostate to Blood Dihydrotestosterone 2003 · 28 citations
    15. Mechanism of Salutary Effects of Finasteride on Post-traumatic Immune/Inflammatory Response Annals of Surgery · 2007 · 18 citations
    16. Persistent Erectile Dysfunction after Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment The World Journal of Men s Health · 2018 · 17 citations
    17. Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases Current Medicinal Chemistry · 2016 · 11 citations
    18. Repurposing steroidogenesis inhibitors for the therapy of neuropsychiatric disorders: Promises and caveats Neuropharmacology · 2018 · 10 citations
    19. Beneficial effects of finasteride on hepatic and pulmonary immune response after trauma hemorrhage in mice Cytokine · 2015 · 1 citations
    20. Pharmacologically altered Androgens, Brain Activation and Response Inhibition in a Stop-Signal Task in Male Heavy Drinkers 2026
    21. A concise review- Development of an analytical method and validation of dutasteride Current Trends in Pharmacy and Pharmaceutical Chemistry · 2025
    22. Medical Management Options for Hair Loss Springer eBooks · 2011
    23. Pharmacodynamic modeling of finasteride, a 5 alpha-reductase inhibitor. PubMed · 1995 · 7 citations
    24. 5 alpha-reductase inhibition by a new synthetic steroid (PM-9) in cultures of Penicillium crustosum. PubMed · 2002 · 1 citations
    25. A population pharmacokinetic model for individualized regimens of finasteride according to CYP3A5 genotype and liver function Journal of pharmaceutical investigation · 2023
    26. 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder Neuropsychopharmacology · 2015 · 110 citations
    27. Dutasteride reduces alcohol’s sedative effects in men in a human laboratory setting and reduces drinking in the natural environment Psychopharmacology · 2014 · 32 citations
    28. SRD5A2 and emerging therapies in androgen-driven disorders Nature Reviews Urology · 2026
    29. Simultaneous Target-Mediated Drug Disposition-Pharmacodynamic (TMDD-PD) Modeling of Finasteride and Dutasteride: Impact of Target Binding and Turnover on Non-linear Pharmacokinetics The AAPS Journal · 2025
    30. Pharmacological Role and Clinical Applications of 5α-Reductase Inhibitors-Review Article for Pharmacists and Healthcare Professionals 2025