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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Lowering testosterone speeds up wound healing in male mice.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Higher DHT in male baldness may protect against prostate cancer.

Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.

Innovative methods are reducing animal testing and improving biomedical research.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Genes and hormones cause hair loss, with four genes contributing equally.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Adjusting estradiol-ANGPT2 levels can promote hair growth in female pattern hair loss.

Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.

Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.

Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

There is no gold standard treatment for hidradenitis suppurativa due to insufficient evidence.

The Shen Bai Hair Growing Decoction may help treat hair loss by promoting hair growth and reducing inflammation.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.