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Hormones and genes affect hair growth and male baldness.

Finasteride may cause kidney damage.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

The document explains how male reproductive hormones work and affect the body.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Estrogen can temporarily slow down hair growth but this can be reversed.

Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Adding a second method to PROTACs could improve cancer treatment.

Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

PGD2 stops hair growth and is higher in bald men with AGA.

Testosterone is crucial for development, growth, and various body functions in mammals.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.