research Receptor Activator of NF-κB Stimulates the Proliferation of Epithelial Cells of the Epidermo-Pilosebaceous Unit
RANK-RANKL signaling is essential for hair growth and skin health.
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research Hair Depigmentation Is a Biological Readout for Pharmacological Inhibition of KIT in Mice and Humans
Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.
research Follicles, Fungi, And Scalp Conditions
Malassezia yeast plays a key role in dandruff and seborrhoeic dermatitis.
research Integrative Approaches for the Management of PCOS: A Review
Combining different treatments can help manage Polycystic Ovary Syndrome (PCOS) effectively.
research Vitamin D Activates Type A Natriuretic Peptide Receptor Gene Transcription in Inner Medullary Collecting Duct Cells
Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.
research The Expansion of Uterus Transplantation to Transgender Women
Doctors are preparing to potentially perform uterus transplants in transgender women, considering technical, hormonal, and ethical factors.
research Finasteride, a 5alpha-Reductase Inhibitor, Blocks the Anticonvulsant Activity of Progesterone in Mice
Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.
research Methylation of SRD5A2 in the Blood as a Novel Biomarker to Predict Sensitivity to 5-ARI Treatment
SRD5A2 methylation in blood can predict how well someone will respond to finasteride treatment.
research Design, Synthesis and Anti-Tumor Evaluation of Novel Thiohydantoin Congeners as Androgen Receptor Antagonists With In Vivo Study
A new compound, 3a, effectively fights prostate cancer better than finasteride.
research Low Disease Activity—Irrespective of Serologic Status at Baseline—Associated with Reduction of Corticosteroid Dose and Number of Flares in Patients with Systemic Lupus Erythematosus Treated with Belimumab: A Real-Life Observational Study
Belimumab reduces disease activity, steroid use, and flares in lupus patients.
research Female Pattern Hair Loss
FPHL is a common, age-related, genetic hair loss with unclear causes and limited treatment options.
research A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss
5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.
research Matrix Effects And Application Of Matrix Effect Factor
Matrix effects in LC-MS can be managed but not completely avoided.
research The Psychological and Aesthetic Impact of Age-Related Hair Changes in Females
Hair loss affects women's self-esteem; treatments like minoxidil can help.
research Polycystic Ovary Syndrome: Features, Diagnostic Criteria, and Treatments
PCOS is a long-term condition that needs more research for better understanding and treatment.
research Androgenic Disorders: Comprehensive Coverage of Syndromes in Women
The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.
research AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis
AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
research Adjuvant Treatment with Oral Minoxidil for Refractory Alopecia Areata to JAK Inhibitors
Combining oral minoxidil with JAK inhibitors helps regrow hair in severe alopecia areata cases.
research Synthesis and Biological Evaluation of Amino-Pyridines as Androgen Receptor Antagonists for Stimulating Hair Growth and Reducing Sebum Production
A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.
research The Post-Finasteride Syndrome: An Overview
Finasteride can cause side effects, some lasting after treatment ends, and may lead to severe depression or suicidal thoughts.
research Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome
The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.
research Alopecia Areata: Gene Expression in Skin Samples from Patients
Alopecia areata involves immune response and gene changes affecting hair loss.
research TGFβ Signaling Regulates Lipogenesis in Human Sebaceous Gland Cells
TGFβ signaling prevents sebaceous gland cells from producing fats.
research Fluorouracil-Induced Reactive Follicular Squamous Cell Carcinoma
research Dutasteride Improves Nocturia but Does Not Lead to Better Sleep: Results from the REDUCE Clinical Trial
Dutasteride can reduce night-time urination but it doesn't improve sleep quality.
research Janus Kinase Inhibitors for Alopecia Areata
JAK inhibitors offer new hope for treating severe alopecia areata.
research Complex Approach to the Treatment of Androgenetic Alopecia in Male Persons with a Poor Prognosis of the Disease
A new method for treating male pattern baldness in men with a low chance of improvement was discussed.
research Health-Related Quality of Life Among Patients With Alopecia Areata: A Systematic Review
People with alopecia areata, a skin disease, generally have a poor quality of life, especially if more of their scalp is affected.
research Decreased Serum Ferritin Is Associated With Alopecia in Women
Low iron levels may be linked to some types of hair loss in women.
research Treatment of Alopecia Areata
No treatment reliably changes Alopecia Areata's course; reassurance and possibly a wig are recommended.