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Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Chemotherapy can cause various skin problems, and recognizing them helps improve patient care.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Transcutol-containing vesicles improve minoxidil's skin penetration and hair growth promotion.

Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.