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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Stress can stop hair growth in mice, and treatments can reverse this effect.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

TSH is usually the only test needed to check thyroid function in primary care.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Skin fat helps with body temperature control and has other active roles in health.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.