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Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Probiotic bacteria improved skin and hair health in aged mice.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.