November 2025 in “Journal of Investigative Dermatology” Alpha-MSH affects mitochondrial function, and MC1R mutations may increase skin aging.
November 2025 in “EXPERIMENTAL ANIMALS” In this murine study, researchers found that topical treatment with Philippine stingless bee propolis increased folliculogenesis, epidermal thickness, and melanogenesis, but not hair length, potentially supporting hair follicle regeneration and melanocyte function in chemotherapy-induced alopecia models.
November 2025 in “The Journal of Immunology” In this study, researchers observed elevated levels of epidermal γδ T cells, keratinocytes, and an upregulation of the BST2 gene among immune cells in C3H/HeJ mice with alopecia areata, suggesting a potential role in disease pathogenesis.
September 2025 in “Cutaneous and Ocular Toxicology” In this study, researchers found no significant differences in serum levels of ferritin, folate, vitamin B12, vitamin D, or thyroid function between patients with scarring alopecia and healthy controls, suggesting these factors may not play a major role in the disease's pathogenesis.
September 2025 in “Online Türk Sağlık Bilimleri Dergisi” This study observed that pediatric patients with diffuse, non-scarring alopecia had significantly lower levels of zinc and folate compared to matched healthy controls, suggesting a possible link between these deficiencies and hair loss in children.
May 2025 in “Frontiers in Genetics” This study reported discovering a novel missense variant in a case of autosomal recessive woolly hair in a 31-year-old Chinese woman, which significantly reduced secretion of the encoded protein, likely leading to disease by impairing its hydrolytic function.
This study found that a hair tonic formulation containing 1.5% light fraction patchouli oil demonstrated strong antifungal activity against Malassezia globosa and promoted hair growth in rabbits, suggesting potential benefits for hair care despite the need for human clinical trials to confirm safety and effectiveness.
April 2025 in “Pharmacy Practice” This study assessed the impact of hormonal contraceptives on liver function in 46 women aged 25-45 and found that contraceptive users, particularly those using combined oral contraceptives, had significantly higher liver enzyme levels compared to non-users, suggesting potential adverse effects that warrant further investigation.
October 2024 in “Journal of the Endocrine Society” This study examined uncharacterized CYP21A2 gene variants related to non-classic congenital adrenal hyperplasia and found that several mutations reduce enzyme activity, which may help improve diagnostic and treatment strategies.
October 2024 in “Journal of the Endocrine Society” This study found that certain CYP21A2 mutations significantly reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia phenotypes, which may aid in enhancing diagnosis and treatment strategies.
August 2024 in “Journal of Cosmetic Dermatology” This study investigates differences in nutritional status, vitamin, and mineral levels between individuals with telogen effluvium and a control group, aiming to understand the nutritional factors involved in this condition.
February 2024 in “International Journal of Research in Dermatology” In this study, researchers examined thyroid function and autoantibody levels in patients with alopecia areata and vitiligo, finding similar rates of thyroid dysfunction and autoantibody presence in both groups, with no significant differences based on ethnicity or gender.
January 2024 in “International journal of chemical research and development (Print)” This study found significant associations between reduced levels of vitamin B12, zinc, and other vitamins, and the occurrence of hair loss in women with alopecia.
October 2023 in “Journal of pharmaceutical investigation” In this study, researchers found that among healthy Korean males, the clearance of finasteride was about 34% lower in individuals with the CYP3A5*3 homozygous allele compared to other genotypes, suggesting dosage adjustments may be necessary considering CYP3A5 and ALT levels to avoid adverse effects.
September 2023 in “Curēus” This study found that individuals with alopecia areata showed differences in otoacoustic emissions, suggesting potential links between the condition and auditory dysfunction, with significant gender and age group variations observed in hearing test results.
April 2023 in “Advanced functional materials” This study created a Wnt3a protein gradient using Multiphoton Microfabrication technology, which improved hair-inductive properties in mouse and human hair dermal papilla cells, suggesting potential applications in hair regeneration research and drug screening.
November 2022 in “Journal of Investigative Dermatology” This study found that patients with COVID-19 induced telogen effluvium experienced significantly greater cognitive deficits, which were strongly associated with increased symptoms of depression, anxiety, and stress.
October 2022 in “The Egyptian Journal of Hospital Medicine” This study found that thyroid dysfunctions were present in a significant number of women with diffuse hair loss, suggesting the importance of investigating thyroid functions in these patients.
COVID-19 patients with hair loss experienced more cognitive issues and these issues were linked to higher levels of depression, anxiety, and stress.
June 2022 in “Frontiers in Genetics” Machine learning is effective in predicting gene functions and their relationships with diseases.
May 2022 in “Endocrine practice” This case report illustrates that high-dose biotin supplementation can cause false thyroid function test abnormalities in vitro, emphasizing the need to assess biotin intake before testing.
January 2022 in “Indian journal of dermatopathology and diagnostic dermatology” This study observed that low serum ferritin and vitamin D levels may contribute to diffuse hair loss in women.
December 2021 in “Research Square (Research Square)” In this study, high expression of S100A4 in glioblastoma was associated with worse patient survival and promoted tumor progression by enhancing pro-tumorigenic vascular functions.
August 2021 in “Oxford University Press eBooks” This chapter discusses various skin functions and structures involved in protection, immune response, and homeostasis, but it reports no new research findings.
This study found no significant differences in iron metabolism-related or thyroid function parameters between women with chronic diffuse hair loss and healthy controls.
January 2021 in “Journal of clinical and cosmetic dermatology” This review highlights the role of the skin's photosensory system in mediating responses to UVA radiation, contributing both to immediate protective effects and to broader circadian and seasonal adaptations, but reports no new experimental results.
January 2021 in “Dermatology Research and Practice” This study will explore skin and hair characteristics of pregnant women and their newborns, examining the relationships between these factors and the newborns' skin maturation over time.
This study found that ocu-miR-205 promotes the apoptosis of dermal papilla cells and the transformation of hair follicles from growth to regression and resting phases in Rex rabbits.
This study found that ocu-miR-205 influences hair follicle density in Rex rabbits by promoting dermal papilla cell apoptosis and transforming hair follicles from growth to resting phases through signaling pathway modulation.
This study found that ocu-miR-205 promotes changes in signaling pathways and shifts in hair follicle phases, affecting Rex rabbit hair density by increasing secondary follicles.