August 2020 in “Research Square (Research Square)” This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients, potentially offering a new therapeutic approach for degenerative diseases.
November 2019 in “Клітинна та органна трансплантологія” This review discusses the functional properties and clinical applications of adipose-derived stem cells in aesthetic medicine and dermatology, but it reports no new clinical results.
The interdisciplinary approach improved the quality of life for a Parkinson's patient and eased staff workload.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified a new cis-regulatory element in the mouse Hr gene that influences its expression in skin and brain cells, highlighting a complex molecular network involved in hair follicle formation.
January 2015 in “D-Scholarship@Pitt (University of Pittsburgh)” This dissertation investigated barriers to clinical translation of adipose-derived mesenchymal stem cell-based vascular grafts, highlighting issues with thrombosis in diabetic patients and proposing alternative cell sources to improve applicability.
August 2026 in “ChemRxiv” This review explores the convergence of functional biomaterials, biosensing, and AI technologies in bioengineering, highlighting applications in cancer modeling and regenerative medicine, while addressing challenges like biofouling and dataset integration.
April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, CRISPR/Cas9-engineered Arabidopsis mutants revealed diverse functional differences among expansin proteins essential for root hair growth, highlighting variability in protein trafficking, cell wall binding, and evolutionary changes in critical residues affecting wall loosening.
February 2026 in “PubMed” This case report describes how a 21-year-old male with alopecia areata and seborrheic dermatitis showed clinical improvements and symptom relief following a tailored, three-month functional nutrition protocol, highlighting potential benefits of addressing root causes in immune-related skin conditions.
September 2025 in “ACS Applied Materials & Interfaces” In this study, composite dressings made from SP nanofibers, Megel hydrogel, and cotton nonwoven significantly accelerated wound healing in diabetic mice, achieving ∼98% closure within 18 days, while enhancing tissue regeneration and reducing inflammation.
July 2025 in “Highlights in Science Engineering and Technology” In this study, researchers found that nanomaterials designed for plastic surgery applications show promising results, including a 95% dynamic wrinkle filling rate and enhanced hair density by 41%; however, challenges like potential long-term safety issues and high production costs must be addressed.
January 2025 in “Elsevier eBooks”
March 2024 in “Organic letters” This study reports that difluoromethyl nitrile oxide can rapidly functionalize various alkenes at room temperature, leading to products that can transform into valuable medicinal chemistry building blocks like CF2H-isoxazolines for bioactive molecule modification.
This study found that PRL-1-overexpressing PD-MSCs reduced adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by secreting IGFBPs and modulating the FAK pathway.
January 2016 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study demonstrates that collagen XVII is crucial for normal glomerular development, is present in normal colon epithelia, and plays a role in carcinogenesis in colorectal and squamous cell cancers.
August 2013 in “Han'gug saengmul gonghag hoeji/KSBB journal” This study found that callus extracts from apple 'Hirosaki' may improve collagen synthesis, hair follicle cell proliferation, and possess significant anti-inflammatory properties.
May 2005 in “Cancer Research” This study found that over-expression of thymosin beta-4 in transgenic mice accelerated wound healing and hair growth, but did not affect tumor progression despite stimulating tumor metastasis.
January 2017 in “Springer eBooks” This review discusses recent advancements in hair follicle regeneration technologies, including the authors' own development of functional hair regeneration through bioengineered follicle germ transplantation, but reports no new clinical results.
660 citations
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December 2011 in “Cell” This study found that distinct low-threshold mechanoreceptors innervate different hair follicle types in mice, suggesting that these follicles serve as unique mechanosensory structures in touch perception.
506 citations
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January 2012 in “Molecular and Cellular Endocrinology” This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.
306 citations
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August 2011 in “Journal of cachexia, sarcopenia and muscle” This study found that GTx-024 significantly increased total lean body mass and improved physical function in healthy elderly men and postmenopausal women, suggesting potential use for muscle wasting conditions.
247 citations
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June 2021 in “Frontiers in Cell and Developmental Biology” This review discusses the role of lncRNA Xist in cell growth regulation and disease development, particularly cancer, and reports no new experimental results.
220 citations
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March 2020 in “Advanced functional materials” This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.
182 citations
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June 2017 in “Biomaterials” This study found that adipose-derived mesenchymal stem cells produced more anti-inflammatory and pro-angiogenic cytokines on electrospun scaffolds, which enhanced wound healing and macrophage activity in a rat model.
179 citations
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April 2012 in “Nature Communications” This study demonstrates the potential of using bioengineered follicles from adult tissue-derived stem cells for fully functional hair regeneration, illustrating possible applications in organ replacement therapy.
176 citations
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February 2006 in “Cancer Research” This study found that loss of Ptch1 function in mouse skin's basal cells is sufficient to rapidly induce tumors resembling human basal cell carcinoma, suggesting Ptch1 as a key tumor suppressor.
163 citations
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November 1976 in “Annals of Internal Medicine” This study found that adults with sickle cell anemia exhibited androgen deficiency due to primary testicular failure, and there was a significant correlation between erythrocyte zinc levels and serum testosterone.
160 citations
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April 2014 in “Drug discovery today” This review discusses the mechanism of action of melatonin in various disorders and suggests its potential for designing new receptor ligands, but reports no new clinical findings.
129 citations
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January 2007 in “Otology & Neurotology” This study found that delivering math1 via an adenovector led to vestibular hair cell regeneration and improved balance function in ototoxin-treated adult mice.
97 citations
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September 2016 in “Reviews in Endocrine and Metabolic Disorders” This review summarizes recent multidisciplinary advances in sebaceous gland research and highlights potential novel therapeutic strategies for skin diseases, but it reports no new clinical results.