Sensory neuron and Merkel-cell changes in the skin happen independently during normal skin maintenance.
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
9 citations,
February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Early regulatory T cells are crucial for normal skin pigmentation.
41 citations,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
January 2025 in “Cellular & Molecular Biology Letters” Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.
82 citations,
May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
August 2023 in “International Journal of Molecular Sciences” Human skin xenografting could improve our understanding of skin development, renewal, and healing.
114 citations,
March 2002 in “Current opinion in oncology/Current opinion in oncology, with cancerlit” Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.
211 citations,
October 2001 in “The FASEB Journal” Noggin is necessary to start the hair growth phase in skin after birth.
17 citations,
August 2019 in “Frontiers in Immunology” Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.
32 citations,
January 2022 in “International Journal of Molecular Sciences” Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
20 citations,
October 2018 in “Aesthetic Plastic Surgery” PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
42 citations,
May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
3 citations,
May 2017 in “Heliyon” Wound healing can help prevent hair loss from chemotherapy in young rats by increasing interleukin-1β signaling.
10 citations,
January 2014 in “Chemical and Pharmaceutical Bulletin” Ethanol pretreatment affects drug penetration through skin and hair follicles.
47 citations,
February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
6 citations,
May 2015 in “Veterinary Clinics of North America: Equine Practice” Horse skin diseases are complex to manage and often require a biopsy for accurate diagnosis and treatment.
28 citations,
April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.
75 citations,
March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
168 citations,
August 2000 in “American Journal of Pathology” Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.
106 citations,
July 2013 in “Advances in wound care” UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.
69 citations,
August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
14 citations,
November 2019 in “Materials” Diamond nanoparticles can penetrate skin and reach hair follicles, useful for imaging applications.
3 citations,
December 2023 in “Cell proliferation” Stuff from umbilical cord stem cells helps skin heal and look younger.
February 2024 in “Frontiers in physiology” Hair follicle stem cells help skin heal and grow during stretching.
29 citations,
April 2000 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” ICAM-1 helps regulate hair growth cycles and skin remodeling.
5 citations,
February 2022 in “Animals” Sodium sulfide slows wound healing, while electric shaving is the safest for preoperative hair removal.