This document supplements a study on androgenetic alopecia, describing materials and methods, and includes figures showing fibrosis in the bulge region of miniaturized hair follicles.
8 citations
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June 2024 in “Pharmaceutics” This study found that using elastic nano-liposomes to deliver palmitoylethanolamide improved its transdermal delivery and enhanced its skincare effects, with minimal cytotoxicity and no allergic reactions observed.
2 citations
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January 2022 in “International Journal of Medical Sciences” In this study, kartogenin promoted hair growth by enhancing cell proliferation and migration in vitro and extended hair length in mice, suggesting its potential as a treatment for hair loss.
2 citations
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August 2021 in “Journal of Clinical Psychopharmacology” This case report describes an 8-year-old girl with ADHD who experienced reversible eyebrow alopecia after initiating atomoxetine treatment, with no further occurrences when the medication was reintroduced.
April 2026 in “ACS Applied Materials & Interfaces” In this study, researchers developed a probiotic-based microneedle system combining Weissella cibaria and clascoterone to target androgenetic alopecia, which in a mouse model improved hair density, vascular regeneration, and reduced inflammation, suggesting a promising treatment approach.
Results are not reported in this abstract, which notes that while Janus kinase inhibitors like baricitinib show therapeutic benefits for alopecia areata, the mechanisms and reliable predictors of response remain unclear.
November 2025 in “Analytical Chemistry” This study developed an ultrahigh-power sonicator to improve protein extraction from hair shafts, followed by advanced proteomic analysis, identifying 239 differentially expressed proteins in fetal growth restriction cases compared to healthy controls, which were validated as potential biomarkers for perinatal diagnostics.
October 2025 in “Dermatologic Surgery” This study found that hair follicles with twisted bulbs demonstrated similar survival rates to intact follicles after transplantation into nude mice, suggesting they may be viable for use in FUE surgery.
September 2024 in “Journal of the American Academy of Dermatology”
August 2024 in “Frontiers in Pharmacology” This report observed that discontinuation of cyclosporine led to complete hair regrowth in a child with alopecia, suggesting a potential link between cyclosporine and hair loss.
May 2024 in “JCI insight” In this study, researchers discovered a dominant variant in the ADAM17 gene that causes hypotrichosis with woolly hair, where the mutation leads to hair follicle stem cell exhaustion and abnormal hair follicles, resulting in alopecia.
This review highlights recent advances in the use of light exposure for health purposes, examining its role in pathology, therapeutic strategies, and molecular changes, as well as discussing future developments in this globally supported field.
April 2023 in “Journal of Investigative Dermatology” This study reports distinctive clinical, trichoscopic, and histopathological features of fibrosing alopecia in a pattern distribution among Chinese patients, suggesting possible racial differences compared to previous studies primarily involving Caucasians.
8 citations
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September 2015 in “Hair transplant forum international” This article highlights the significant hair transplant results achieved with the potentially obsolete FUT technique and includes varied expert opinions on its efficacy, but it reports no new clinical findings.
November 2025 in “Indian Journal of Plastic Surgery” In this study, researchers found that using the FUE method, performed by surgeons instead of technicians, allows for more precise follicular unit extraction than the traditional FUT method, potentially improving outcomes and donor area utilization in hair transplantation.
60 citations
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November 2009 in “General and Comparative Endocrinology” The researchers reported that during early embryogenesis and larval development in Silurana tropicalis, inhibiting steroidogenic enzymes cyp19 and srd5beta affects genes related to thyroid and reproductive systems.
July 2025 in “International Journal of Biological Macromolecules” Fucoidan may help regrow hair and reduce inflammation in hair loss.
December 2024 in “DIET FACTOR (Journal of Nutritional & Food Sciences)” This study reports that fenugreek seed extract (Furocyst®) improved body weight, ovarian cysts, ovary size, hair growth, and menstrual regularity in women with PCOS, indicating its potential as an effective phytotherapeutic option for managing the condition.
4 citations
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December 2017 in “Journal of zoo and wildlife medicine” This study proposes that seasonal alopecia and reproductive changes in six female fossas at the San Diego Zoo may be linked to hormonal changes associated with reproductive activity.
179 citations
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December 2004 in “Journal of The American Academy of Dermatology” This study observed that frontal fibrosing alopecia in postmenopausal women involves selective follicular inflammation, and finasteride treatment may slow disease progression, suggesting a potential androgen-related component.
May 2015 in “Journal of the American Academy of Dermatology” Certain drugs and supplements may contribute to hair loss in the frontal hairline in older women.
91 citations
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July 2022 in “Frontiers in Endocrinology” This study reported that Chinese women with PCOS exhibited diverse lipid profiles based on different characteristics, which may help understand their increased risk of cardiovascular disease.
63 citations
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April 1985 in “Journal of the American Academy of Dermatology” This study observed that topical PUVA treatment led to excellent or good hair regrowth in 45.4% of patients with alopecia areata, though many experienced relapse after treatment stopped.
35 citations
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May 2008 in “Drug and Alcohol Dependence” Female mice are less affected by certain substances that alter alcohol consumption compared to male mice.
16 citations
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September 1997 in “Oral surgery, oral medicine, oral pathology, oral radiology and endodontics” This case analysis suggests that while dental foci may rarely contribute to alopecia areata, confirming this link requires observing full recovery after removing the dental cause.
6 citations
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March 1986 in “PubMed” This case study describes a 19-year-old female patient who gained 13 kg and experienced hair changes while on valproic acid, and partially lost weight after reducing the dosage, but hair changes persisted.
4 citations
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August 2023 in “Journal of Investigative Dermatology” Certain genes influence the direction of hair whorls on the scalp.
2 citations
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May 2023 in “Journal of Immunotherapy” In this case study, a 65-year-old male with hepatocellular carcinoma treated with the PD-1 inhibitor Sintilimab developed alopecia universalis alongside significant tumor regression and complete remission, highlighting a rare immune-related adverse event with effective anti-tumor outcomes.
2 citations
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February 2023 in “International Journal of Cosmetic Science” In this study, evidence suggested that hair loss occurs more frequently in multi-hair follicular units on the scalp, particularly in men.
1 citations
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March 2023 in “Journal of Ultrasound in Medicine” In this study, ultrasound showed promise in differentiating trichilemmal cysts from epidermoid cysts, suggesting potential value for clinical management.